摘要
六味地黄方传统用于滋阴补肾,因此被认为具有抗衰老的作用。但该方对动物的生存寿命和衰老生化指标有何影响,特别是全方和拆方的作用未见报道。本文用家蝇为动物模型,分别饲给六味地黄全方和两个拆方。
The whole recipe of Liuwei Dihuang Decoction (LD) was divided into two parts: 'three tonics' consisting of Radix Rehmanniae Preparata 8, Fructus Corni 4, Rizoma Dioscoreae 4; and 'three purgatives' consisting of Cortex Moutan Radicis 3, Poria 3, and Rhizoma Alismatis 3. The effects of decoctions of whole recipe and two partial recipes were compared on the houseflies' life span and some biochemical indices (SOD activity, contents of lipofuscin and pretein in brain). The results showed that both 3% and 1% Liuwei Dihuang Decoction significantly prolonged the average life span, increased the brain SOD activity and the content of protein, and lowered the content of lipofuscin. 'Three tonics' and 'three purgatives' (3%) neither increased the average life span, nor promoted any of the biochemical indices against senescence. The results led to the conclusion that both of the individual partial recipes ('three tonics', 'three purgatives') did not have the effect against senescence, but the combination of the two partial recipes has the effect against senescence.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1990年第4期246-248,共3页
Journal of China Pharmaceutical University
