摘要
目的 :探讨六味地黄发酵液的抗肿瘤和对化疗药物的减毒作用。方法 :采用小鼠腋下接种肿瘤细胞法观察抗肿瘤作用 ,采用环磷酰胺法造成白细胞减少 ,观察六味地黄发酵液对外周血白细胞数的影响。结果 :六味地黄发酵液对小鼠肝癌H2 2 的生长具有显著抑制作用 (P <0 .0 5) ,而六味地黄煎剂无明显抑瘤作用 ;六味地黄发酵液和六味地黄煎剂对环磷酰胺造成的小鼠骨髓抑制 ,均有升高外周血白细胞的作用 (P <0 .0 1 )。结论
Objective: It is to observe the anticancer activity and detoxification effect of fermented Liuweidihuang (LWDH). Methods: Tumor cells were transplanted to the peritoneum of the mice, which were produced to a model of toxicity to bone marrow with cyclophosphamide. Then the mice were treated with LWDH and the number of WBC in serum was determined. Results: The growth of H 22 was markedly inhibited in the group, which were treated with fermented LWDH ( P <0.05), but Liuweidihuang decoction had not markedly anticancer functions. Both fermented LWDH and Liuweidihuang decoction had the function of increasing the number of WBC in serum ( P <0.01). Conclusion: Fermented LWDH has anticancer function. It can decrease the toxic action of chemotherapy.
出处
《现代中西医结合杂志》
CAS
2002年第18期1753-1754,共2页
Modern Journal of Integrated Traditional Chinese and Western Medicine
