摘要
传统中医理论认为六味地黄方是以肝肾之阴为主的补阴代表方剂,方中以熟地,山茱萸,山药为补肝、肾、脾三阴之药,简称“三补”,以泽泻,丹皮,茯苓为“三泻”。
The antihypoxia, hypolipid of Liuwei Dihuang Decoction (LD) and partial recipes (PR_(?)) were studied. The results showed that 20, 29 ml / kg, po of LD could antagonize hypoxia in mice significantly. At higher dose (29 ml / kg, po) LD also had antihypoxia action in mice with the pretreatment of isoproterenol. All PR_(?) had no effect on antihypoxia. LD (20 mg/kg, po Bid) and PR_2 (Cortex Moutan Radicis, Poria, Rhizoma Alismatis), PR_3 (Rhizoma Alismatis, Radix Rehmanniae Preparata) and PR_4 (Fruclus Corni, Cortex Moutan Radicis) decreased total cholesterol (TC) levels of the experiment hyperlipidemia and increased siginificantly (HCL-C) / TC in mice, namely high density lipoprotein cholesterol (HDL-C) was relatively elevated. LD and all PR_(?) showed no effect on the weights of spleen and liver, but LD and PR_1 (Radix Rehmanniae Preparata, Fructus Corni, Rhizoma Dioscoreae) and PR_3 decreased the fat content in the liver.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1990年第4期241-243,共3页
Journal of China Pharmaceutical University
关键词
六味地黄煎剂
药理
小鼠
降血脂
Luiwei Dihuang Decoction
Antihypoxia
Hypolipid
Partial recipes