摘要
目的：研究临界性高血压对左心室肥厚及左心室舒张功能的影响。方法：本文应用无创动态血压及二维彩色多普勒超声心动图检测方法对照研究９２例临界高血压患者左心室重量指数（ＬＶＭＩ）及舒张功能与血压水平及血压节律的关系。结果：临界性高血压组左心室肥厚发生率１８．５％，ＬＶＭＩ与对照组相比为１０７．２±１３．５ｇ比９２．５±１１．６ｇ（Ｐ＜０．０１），ＬＶＭＩ与昼间收缩压及昼间收缩压负荷值相关性最显著（ｒ分别为０．３０及０．２８，Ｐ＜０．０１），与２４小时收缩压及收缩压夜间昼间比值亦有较好的相关性（ｒ分别为０．２５及０．２２，Ｐ＜０．０５），临界性高血压组左心室舒张功能明显受损。结论：临界性高血压已不同程度的存在左心室结构及功能异常，收缩压水平及昼夜节律异常是左心室受累的主要因素。
Objective:To study the effect of borderline hypertension on the left ventricular hypertrophy and left ventricular diastolic function. Methods:Doppler echocardiography and ambulant blood pressure(ABP) unit were used in 92 borderline hypertensive patients and 36 normotensive subjects to investigate the left ventricular mass index (LVMI),left ventricular diastolic function and 24 hour ABP,respectively. Results:The left ventricular hypertrophy were found in 17 of 92 borderline hypertensive patients(18 5%).The LVMI in borderline hypertension group was significantly higher than in normotensives (107.2±13.5 g vs. 92.5±11.6 g, p <0.01).In the borderline hypertension group LVMI was closely correlated with daytime systolic blood pressure (SBP) and load value of daytimes SBP( r =0.30 and 0.28,respectively, p <0.01),it also correlated to the 24 hour SBP and night/day SBP ratio ( r = 0.25 and 0.22,respectively, p <0.05).The left ventricular diastolic function were obviously damaged in borderline hypertension group. Conclusion:The study suggests that left ventricular structure and function are impaired in borderline hypertensive patients.SBP level and the day night rhythm disorder are responsible for the left ventricular involvement.
出处
《中国循环杂志》
CSCD
北大核心
1997年第4期267-269,共3页
Chinese Circulation Journal
关键词
临界性
高血压
左心室肥厚
舒张功能
动态血压
Borderline hypertension
Left ventricular hypertrophy
Diastolic function
