摘要
目的 :了解无症状临界性高血压患者是否有冠状动脉功能异常。方法 :经食管超声心动描记术研究 2 0例正常人 (正常对照组 )及 17例无症状临界性高血压患者 (临界性高血压组 )的冠状动脉血流储备 (CFR)。以潘生丁静脉注射后和静息时舒张期的最大血流速度比率 (D/R PDV)和收缩期最大血流速度比率 (D/R PSV )作为CFR指标。结果 :1两组受检者静息时的 PDV无显著性差异〔(43± 10 ) m m/s∶ (46± 8) mm /s,P >0 .0 5〕;2静脉注射潘生丁后临界性高血压组的 D/R PDV、D/R PSV较正常对照组明显减少 ,两组之间有显著性差异 (D/RPDV:2 .2 5± 0 .36∶ 2 .86± 0 .42 ,D/R PSV:2 .0 0± 0 .2 6∶ 2 .5 6± 0 .41,P<0 .0 5 )。结论 :无症状临界性高血压患者 CFR能力降低。
Objective:To investigate whether functional abnormalities in coronary vasomotion are present in young men with borderline hypertension. Method:Coronary blood flow reserve (CFR) of normal subjects (groupⅠ:n=20) and matched asymptomatic young men with borderline hypertension (groupⅡ:n=17) were studied with transesophageal Doppler echocardiography (TEE) technique. The ratio of dipyridamole to rest peak diastolie velocity (D/R PDV)and dipyridamole to rest peak systolic velocity (D/R PSV) were considered as indices of CFR. Result:①There were no difference of PDV between two groups in rest.〔(43±10)mm/s vs (46±8)mm/s,P> 0.05 ).②D/R PDV and D/R PSV were significantly less in group Ⅱ verse group Ⅰ (D/R PDV: 2.25 ± 0.36 vs 2.86 ± 0.42 , D/R PSV : 2.00 ± 0.26 vs 2.56 ± 0.41 ,P< 0.05 ) after dipyridamole infusion.Conclusion:These results demonstrate that reduced coronary reactivity presents in young asymptomatic peoples with borderline hypertension.
出处
《临床心血管病杂志》
CSCD
北大核心
2000年第6期270-272,共3页
Journal of Clinical Cardiology
关键词
临界性高血压
冠状动脉血流储备
超声心动图
Borderline hyptertention Coronary blood flow reserve Transesophageal echocardiography
