摘要
目的建立中药复方制剂姜香安胃软胶囊(高良姜、木香、干姜)的质量标准控制方法。方法采用薄层色谱法对本品中的高良姜、干姜、木香进行定性鉴别;用高效液相色谱法测定制剂中木香烃内酯、去氢木香烃内酯的含量。结果木香烃内酯在0.103～1.030μg(r=0.999 5,n=7)范围内线性良好,平均回收率为97.27%,RSD=1.10%;去氢木香烃内酯在0.126～1.260μg(r=0.999 6,n=7)范围内线性良好,平均回收率为97.90%,RSD=1.05%。结论该方法准确、可靠,可用于控制姜香安胃软胶囊的质量。
OBJECTIVE To establish the controlling methods for quality standard of jiangxiang Anwei Soft Capsules（Rhizo- ma Alpiniae Officinari, Rhizorna Zingiberis, Radix Aucklandiae ）. METHODS Rhizorna Alpiniae Officinari, Rhizoma Zingiberis, Radix Aucklandiae were identified by thin--layer chromatography（TLC）. The contents of costunolide and de- hydro--costunolide were determined by High Performance Liquid Chromatography （HPLC） together. RESULTS Consimili- tude showed a good linear relationship at the range of 0. 103~1. 030μg（ r：0. 999 5, n=7）, the average recovery was 97.27%, RSD was 1.10 % ;Dehydro-costunolide showed a good linear relationship at the range of 0. 126~1. 260 μg（r= 0. 999 6, n= 7）, the average recovery was 97.90%, and RsD was I. 05%. CONCLUSION This method is accurate, reliable, and can be used for quality control of Jiangxiang Anwei Soft Capsule.
出处
《南京中医药大学学报》
CAS
CSCD
北大核心
2013年第1期75-77,共3页
Journal of Nanjing University of Traditional Chinese Medicine
