摘要
研究8-MOP与ATRA单独及联合应用对Mc3细胞克隆的影响。方法。软琼脂克隆法。结果：照组细胞克隆形成率为53．1％,经IC308-MOP与ATRA单独及联合作用5－d以后，克隆形成率降低为8-MOP组0．9％，ATRA组35.1％，联合用药组3.2％。结论：8－MOP与ATRA单独及联合应用Mc3细胞克隆形成率降低，有可能使Mc3细胞的转移能力下降。
To study the effects of 8-MOP or/and ATRA on Mc3 cell clonogenicity.Methods: The clonogenicity of Mc3 cells was as-sayed by clonogenic assay after the cells had beenfreated with 8-MOP,ATRA or 8-MOP with A-TRA at the dosage 0f IC30 Results: The clono-genicity of the cells was 53%, 0. 9%,35. 1%,and3. 2% for control, 8-MOP, ATRA and 8-MOPwith ATRA treated cells respectively. Conclu-sion: 8-MOP or/and ATRA may inhibit clono-genicity of Mc3 cells.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
1999年第6期465-466,共2页
Journal of Practical Stomatology
基金
国家自然科学基金!39370740
