摘要
目的观察左旋氨氯地平与厄贝沙坦单用及联合对2型糖尿病并发肾病及高血压患者的降压疗效及其对尿白蛋白(Alb)的影响。方法将48例患者随机均分3组,A组口服左旋氨氯地平5mg,1次/d,B组口服厄贝沙坦150mg,1次/d,C组口服左旋氨氯地平5mg及厄贝沙坦150mg,1次/d,疗程为8周。结果3组治疗后血压均显著降低,尿Alb排泄量A、B组无明显变化,C组明显降低。结论左旋氨氯地平、厄贝沙坦联合应用时降压及改善蛋白尿较单用时更好。
Objetive To observe the effects of levoamlodipine alone and irbesartan alone and levoamledipine combined with irbesartan on nephropathy,hypertension and urinary albumin caused by diabetes mellitus, Methods 48 patients were randomly divided into 3 groups： group A received levoamlodipine 5 mg once a day, Group B received irbesartan 150 mg once a day. Group C received levoaralodipine 5 mg and irbesartan 150 mg once a day. The treatment time was 8 weeks. Results After 8 weeks hypertension in the three groups was significantly decreased. Urinary albumin in Group A and Group B had no changes but was decreased significantly in Group C. Conclusion The effects of levoamlodipine combined with irbesartan on hypertension and urinary albumin were better than those of either a single drug.
出处
《四川医学》
CAS
2009年第6期854-855,共2页
Sichuan Medical Journal
关键词
左旋氨氯地平
厄贝沙坦
糖尿病肾病
高血压
肾功能
levoamlodipine
irbesartan
diabetic nephropathy
hypertension
kidney function
