摘要
目的探讨烧伤患者T淋巴细胞亚群与血常规项目的相关性及危险因素分析。方法选取医院就诊的烧伤患者70例为烧伤组,另选取同期30例健康体检者为对照组,分别检测两组研究对象的T淋巴细胞亚群与血常规项目水平进行比较分析。结果烧伤组CD3^(+)T、CD4^(+)Th及CD8^(+)Ts水平均显著低于对照组(均P<0.05)。烧伤组PLT水平显著高于对照组,而烧伤组RBC及HGB水平显著低于对照组(均P<0.05)。烧伤组WBC、NEUT百分比及NEUT绝对值水平显著高于对照组,而烧伤组LYM百分比水平显著低于对照组(P<0.05)。Logistic回归分析结果显示,WBC及NEUT绝对值是烧伤患者的危险因素,而CD4^(+)Th及HGB则为保护因素。结论烧伤患者与T细胞亚群异常免疫紊乱密切相关,同时也需要重视血常规等项目的危险因素,联合检测有助于烧伤病情的正确评估及有效诊疗。
Objective To explore the correlation between T lymphocyte subsets and blood routine items in burned patients and analyze the risk factors.Methods Seventy burn patients in the hospital were selected as the burn group,and 30 healthy physical examination subjects during the same period were selected as the control group.The T lymphocyte subsets and blood routine item levels of the two groups were tested for comparison and analysis.Results The levels of CD3^(+)T,CD4^(+)Th and CD8^(+)Ts in the burned patients group were significantly lower than those in the control group(all P<0.05).The levels of PLT in the burned patients group were significantly higher than those in the control group,while the levels of RBC and HGB in the burned patients group were significantly lower than those in the control group(all P<0.05).The levels of WBC,NEUT percent and NEUT absolute value in the burned patients group were significantly higher than those in the control group,while the levels of LYM percent in the burned patients group were significantly lower than those in the control group(all P<0.05).Logistic regression analysis showed that WBC and NEUT absolute value were risk factors for burned patients,while CD4^(+)Th and HGB were protective factors.Conclusion Theburned patients are closely related to abnormal immune disorders ofT cell subsets.At the same time,attention should be paid to the riskfactors of blood routine.Joint detection can help to correctly evaluatethe condition of burn and effectively diagnose and treat it.
作者
王海延
邹光美
黄朝任
陆颖
吴博文
WANG Haiyan;ZOU Guangmei;HUANG Chaoren;LU Ying;WU Bowen(Department of Clinical Laboratory,The First People’s Hospital of Yulin,Yulin Guangxi 537000,China;Department of Clinical Laboratory,Yulin Traditional Chinese Medicine Hospital,Yulin Guangxi 537000,China)
出处
《中国卫生标准管理》
2021年第9期74-76,共3页
China Health Standard Management
基金
广西玉林市科学研究与技术开发计划项目(玉市科20180104)。
关键词
烧伤患者
T淋巴细胞亚群
免疫紊乱
血常规
检测
危险因素
burn patients
T lymphocyte subsets
immune disorder
routine blood test
detection
risk factors
