摘要
目的:探讨大面积烧伤患者T淋巴细胞亚群变化及其临床意义。方法:采用直接免疫荧光法,应用流式细胞仪,检测45例烧伤患者及15例健康人外周血CD3+T细胞、CD4+T细胞、CD8+T细胞的数值及CD4+/CD8+比值。结果:与正常对照组比较,CD4+细胞数明显降低(P<0.05);CD4+/CD8+比值明显降低(P<0.05)。结论:烧伤患者外周血中的T淋巴细胞亚群在发病机制中起重要作用。
Objective Large area of burns patients T lymphocyte subsets change and its clinical significance. Methods Using direct immun of luoreseence, the value of CD3 ＋ T cells,CD4＋ T cells,CD8＋ T cells and CD4 ＋/CD8＋ in 45 eases of burn patients and 15 healthy people＇s Peripheral blood were detected by FCM. Results With the normal control group, CD4＋ cells decreased significantly （ P 〈 0.05 ） ; CD4 ＋/CD8＋ ratio decreased significantly（ P 〈0. 05 ）. Conclusion Burn patients with the T lymphocyte subsets in the pathogenesis of play an important role.
出处
《实用医技杂志》
2008年第21期2745-2746,共2页
Journal of Practical Medical Techniques
