摘要
目的了解2015-2020年流感流行季北京市流感流行特征。方法使用北京市2015-2020年流感样病例(influenza-like illness,ILI)和流感病原学监测数据,分析流感流行趋势和流感病毒流行特征。结果2015年第27周至2020年第26周共涉及5个流感流行季,流感样病例百分比(percentage of influenza-like illness,ILI%)为1.58%。共检测ILI标本96892件,流感病毒核酸阳性率为16.32%,其中A(H3N2)亚型6474件(40.89%)、甲型H1N14410件(27.86%)、乙型Victoria系3290件(20.78%)、乙型Yamagata系1597件(10.09%)。ILI周报告数、ILI%与流感病毒阳性率变化趋势基本一致(r=0.796,P<0.001;r=0.808,P<0.001)。2017-2018年和2018-2019年流行季活跃期较长。2017-2018、2018-2019年流行季ILI周报告数较高(49628人次和71555人次),核酸阳性率峰值较高(58.51%和57.08%)。结论2015-2020年北京市流感流行符合北半球流行特征,其中2017-2018和2018-2019流行季活跃期较长、流行水平较高,且各流行季优势毒株不同。
Objective To analyze epidemiological characteristics of influenza in Beijing during 2015-2020 influenza seasons.Methods Weekly numbers of cases with influenza-like illness and weekly data of virologic surveillance was used to analyze epidemic trend and characteristics of influenza.Results From June 26,2015 to June 28,2020,influenza-like illness(ILI)was 1.58%.A total of 49868 pharyngeal swab samples were collected from ILI cases,and positive rate of influenza virus nucleic acid was 16.32%by real-time PCR.Of these positive samples,40.89%(6474)were A(H3N2),27.86%(4410)were A(H3N2),20.78%(3290)were B/Victoria lineage,and 10.09%(1597)were B/Yamagata lineage.There were correlation between ILI and positive rate of influenza virus(r=0.796,P<0.001),and ILI percentage and positive rate were also correlated(r=0.808,P<0.001).The active duration in 2018-2018,2018-2019 influenza seasons were longer.Weekly numbers of influenza-like illness cases of 2017-2018,2018-2019 influenza seasons were higher(49628 and 71555),peak value of positive rate in the above seasons was higher(58.51%and 57.08%).Conclusions The epidemic characteristics of influenza during 2015-2020 years was in accordance with the temperate regions of the northern hemisphere.There were longer active period and higher epidemic level in 2017-2018,2018-2019 influenza seasons.The dominant influenza virus subtypes varied in the different seasons.
作者
马春娜
吴双胜
张莉
张奕
孙瑛
段玮
杨鹏
王全意
Ma Chunna;Wu Shuangsheng;Zhang Li;Zhang Yi;Sun Ying;Duan Wei;Yang Peng;Wang Quanyi(Institute for Infectious Disease and Endemic Disease Control,Beijing Center for Diseases Control and Prevention,Beijing Research Center for Preventive Medicine,Beijing 100013,China;Office of Beijing Center for Global Health,Beijing Center for Diseases Control and Prevention,Beijing100013,China)
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
2021年第1期44-48,共5页
Chinese Journal of Experimental and Clinical Virology
关键词
流感
流感样病例
亚型
监测
Influenza
Influenza-like illness
Subtypes
Surveillance
