期刊文献+

PRF治疗牙龈退缩的对照研究 被引量:8

Controlled clinical study of treatment of gingival recession using Platelet-Rich-Fibrin(PRF) membranes with connective tissue graft
原文传递
导出
摘要 目的:通过对比观察采用Choukroun's富血小板纤维蛋白膜(PRF膜)和采用结缔组织瓣治疗牙龈退缩的临床效果。方法:临床上选取有牙龈退缩且有意愿进行手术治疗的患者13例,分为PRF膜组和对照组,分别实施手术治疗,在术前、术后3个月测量牙周袋深度(PD)、角化龈宽度(KTW)以及牙龈退缩量,并对结果进行对照分析。结果:两组数据中牙周袋深度术前术后比较均无显著性差异(P≤0.05);角化龈宽度和牙龈退缩量术前术后比较均有显著性差异(P≥0.05)。角化龈宽度术后比较两组之间无显著性差异(P≥0.05);牙龈退缩量对照组小于PRF组(P≤0.05)。结论:PRF膜(富血小板纤维蛋白)治疗牙龈退缩的根面覆盖量虽不及结缔组织瓣+冠向复位组,但对于MillerⅠ°、Ⅱ°同样可以达到很好的根面覆盖效果;且术后角化龈宽度明显增加,和膜龈组之间无显著性差异(P>0.05)。 Objective:To provide the Clinical evaluation of Choukroun's platelet-Rich-Fibrin(PRF) Membranes in treatment of gingival recessions contrasting connective tissue graft. Method:Choose 13 patients of Gingival Recessions intend to surgical treatment, measure periodontal pocket depth, width of attached gingival and loss of attachment level in preoperative and postoperative 3 months. TO contrast the Clinical effect of Choukroun's PRF Membranes in Gingival Recessions. Result:It has no statistically significant change in Periodontal pocket depth by surgery for both groups(P〉0.05);The width keratinized gingival and vertical gingival recession depth are increasing after operation, have statistically significant changes compared with pre-operation(P〈0.05).It has no statistically significant change after operation between groups for width keratinized gingival(P〉0.05);It was fewer for the PRF group in comparison with the control group for vertical gingival recession depth(P〈0.05).Conclusion:For root coverage, it can be achieved a better clinical effects by Platelet-Rich-Fibrin(PRF) membranes,especially for Miller ClassⅠorⅡ.
出处 《临床口腔医学杂志》 2016年第4期230-232,共3页 Journal of Clinical Stomatology
基金 北京市首都卫生发展科研专项项目基金项目(2011-5031-01)
关键词 富血小板纤维蛋白 牙龈退缩 结缔组织瓣 Platelet-rich-fibrin(PRF) Gingival recession Connective tissue graft
  • 相关文献

参考文献10

  • 1曹采方.临床牙周病学[M].北京:北京大学医学出版社,2009:110.
  • 2David M. Dohan,Joseph Choukroun,Antoine Diss,et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part I: Tech- nological concepts and evolution [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 101 :E37-44.
  • 3David M. Dohan,Joseph Choukroun,Antoine Diss,et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate.Part III: Leu- cocyte activation: A new feature for platelet concentrates? [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 101 :E51-55.
  • 4David M. Dohan,Joseph Choukroun,Antoine Diss,et al. Platelet-rich fibrin (PRF):A second-generation platelet concentrate. Part II: Platelet -related biologic features[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 101:E45-50.
  • 5Ling He,Ye Lin,Xiulian Hu,et al. A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2009,108:707-713.
  • 6Jos eph Choukroun,Antoine Diss,Alain Simonpieri,et al. Platelet- rich fibrin (PRF): A second-generation platelet eoneentrate.Part V: Histologic evaluations of PRF effects on bone allograft maturation in sinus lift [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 101:299-303.
  • 7Giannobile WV,Whitson SW,Lynch SE. Non-coordinate control of bone formation displayed by growth factor combinations with IGF-I [J].J Dent Res, 1997, 76:1569.
  • 8Dohan Ehrenfest DM,Rasmusson L,Albrektsson T. Classification of platelet concentrates:from pure platelet-rich plasma (P-PRP) to leu- cocyte- and platelet-rich fibrin (L-PRF)[J]. Trends Biotechnol, 2009,27:158e67.
  • 9Pierce GF,Mustoe TA,Altroek BW,et al.Role of platelet-derived growth factor in wound healin[J]. J Cell Biochem,1991,45:319-326.
  • 10Aroca S,Keglevich T,Barbieri B,et al.Clinical Evaluation of a Modi- fied Coronally Advanced Flap Alone or in Combination With a Platelet-Rich Fibrin Membrane for the Treatment of Adjacent Mul- tiple Gingival Recessions:A 6-Month Stud [J].J Periodontal,2009,80: 244-252.

共引文献8

同被引文献45

引证文献8

二级引证文献32

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部