摘要
目的:探究阿托伐他汀对脑梗死后抑郁的影响。方法:回顾性分析400例脑梗死患者的资料并分组,随访3个月,分析治疗前、后汉密尔顿抑郁量表(HAMD)评分。结果:强化、标准降脂组治疗前、后HAMD评分无显著差异(P>0.05)。治疗3个月后,女性组HAMD评分高于男性(P<0.05),但组间阿托伐他汀剂量、血脂水平无统计学差异(P>0.05)。结论:阿托伐他汀不影响脑梗死后抑郁症状,女性脑梗死后抑郁情况与阿托伐他汀剂量及血脂水平无关。
Objective ：To study the atorvastafin in depressive symptoms among cerebral infarction patients .Methods ：Collect the data of 400 targeted patients and group them .Hamilton Depression Rating Scale（HAMD）was tested before and after treatment and analysized after 3-months treatment .Results：No significant difference in HAMD score between intensive and standard lipid lowering group （P〉 0 .05） .The HAMD scores in female group was higher than that in male group after treatment （P〈 0 .05） ,but not the lowering level of lipid and different dosage of atorvastatin （P〉0.05） .Conclusion：The use of atorvastatin will not influence depressive symptoms in cerebral infarction patients .The female patients’depressive symptoms is not related to the level of lipid and the dosage of atorvastatin .
出处
《医学理论与实践》
2014年第11期1403-1404,1418,共3页
The Journal of Medical Theory and Practice
关键词
阿托伐他汀
降脂
脑梗死
抑郁
Atorvastatin
Lipid lowering
Cerebral infarction
Depression
