摘要
目的探讨中青年与老年脑梗死患者的病因、危险因素的异同。方法对2011年1—11月我科收治的112例中青年脑梗死患者和150例老年脑梗死患者的临床资料进行分析,比较两组的病因类型及危险因素。结果据TOAST病因分型,中青年组和老年组均以小动脉闭塞为最常见,两组小动脉闭塞发生率比较,差异无统计学意义(P>0.05);心源性栓塞、大动脉粥样硬化及原因不明的缺血性卒中发生率比较,差异均无统计学意义(P>0.05)。而中青年组脑梗死患者其他原因引起的缺血性卒中发生率显著高于老年组患者,差异有统计学意义(P<0.05)。中青年组主要危险因素为:高血压、吸烟和不良生活方式,而老年组主要危险因素为:高血压、心脏疾病、高脂血症和糖尿病。中青年组患者危险因素中高血压、心脏疾病、吸烟及不良生活方式所占比例与老年组比较,差异均有统计学意义(P<0.01);而其他危险因素比较,差异均无统计学意义(P>0.05)。结论中青年与老年脑梗死患者在病因学和危险因素等方面有其特殊性,及时干预危险因素,并针对病因进行治疗,对脑梗死的预防和预后具有重要的临床价值。
Objective To investigate the risk factors and etiology of cerebral infarction in young,middle-aged and elderly people.Methods Clinical data of 112 cases of young and middle-aged people and 150 cases of elderly people with cerebral infarction were retrospective analyzed.Etiology and risk factors were compared between the two groups.Results According to TOAST subtypes,SAO was the most commonly seen in young and middle-aged group and elderly group,and the difference of SAO incidence between the two groups was not statistically significant（P0.05）.The incidences of CE,LAA and UND also did not show statistically significant differences（P0.05）.The incidence of SOE in young and middle-aged group was significantly higher than that of the elderly group（P0.05）.The risk factors for young and middle-aged group were hypertension,smoking and adverse lifestyle.While the risk factors for elderly group were hypertension,heart disease,hyperlipidemia and diabetes.The proportion of hypertension,heart disease,smoking and adverse lifestyle in young and middle-aged group showed statistically significant difference compared with elderly group（P0.01）.While other risk factors showed no statistically significant difference（P0.05）.Conclusion Young,middle-aged and elderly infarction patients have their own specific characteristics.Timely intervention of risk factors and treatment of etiology is of great importance for the treatment and prognosis of infarction.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第17期1940-1942,共3页
Chinese General Practice
关键词
脑梗死
青年人
中年人
老年人
病因
危险因素
Brain infarction
Young people
Middle aged
Aged
Etiology
Risk factors
