摘要
以酸性离子液体[Hmim]HSO4为催化剂,对羟基苯甲酸和正丙醇为原料合成了尼泊金丙酯,采用红外光谱和液相色谱-质谱对产品结构进行表征。考察了酸醇物质的量比、反应时间、反应温度、催化剂用量等对反应的影响,确定最佳反应条件为:酸醇物质的量比为1∶3、催化剂用量为反应物总质量的4%、反应时间3 h、反应温度90℃,在此条件下,尼泊金丙酯收率达91.8%。催化剂重复使用5次后,其催化活性基本不变。
With p-hydroxybenzoic acid and n-Propanol as raw materials,synthesis of propylparaben catalyzed by acidic ionic liquid [Hmim]HSO4 was researched.The structure of propylparaben was characterized by IR and LC-MS.The effects of the molar ratio of p-hydroxybenzoic acid to n-Propanol,reaction time,reaction temperature and catalyst amount on the yield of propylparaben were investigated.The optimal conditions were obtained as follows： the molar ratio of p-hydroxybenzoic acid to n-Propanol 1：3,the catalyst amount of reactant total mass 4 %,reaction time 3 h,reaction temperature 90 ℃.Under above conditions,the yield of the propylparaben reached 91.8 %.The catalytic activity of [Hmim]HSO4,was remained mostly after reused for 5 times.
出处
《广东化工》
CAS
2013年第3期18-19,17,共3页
Guangdong Chemical Industry
基金
茂名市重点科技计划项目(20101072)
关键词
尼泊金丙酯
酸性离子液体
催化
合成
propylparaben
acidic ionic liquid
catalysis
synthesis
