摘要
应用放免法 (RIA)测定 64例原发性高血压病Ⅱ期患者 (其中伴房颤患者 34例 )血清内皮素 (ET)与心钠素 (ANP)含量 ,并以 34名健康者作对照。高血压病患者血清ET与ANP均高于正常对照 (P <0 .0 1)。高血压病伴房颤患者血清ANP虽然比不伴房颤患者高 ,但无统计学意义 ;而前者血清ET则明显高于后者 (P <0 .0 1) ,即高血压病伴房颤患者ET水平高。结果提示 :高血压病伴房颤患者的血流动力学异常 。
Plasma levels of endothelin(ET) and atrial natriuretic peptide(ANP) were measured with radioimmunossay(RIA) in 34 healthy controls and 64 patients with essential hypertension(EH), among them 34 patients with auricular fibrillation(AF). The plasma levels of both ET and ANP were significantly higher in the patients than in the healthy controls(P<0.01).The ANP levels of EH patients with AF were higher than those of patients with no-AF, but no statistic difference was found. The ET levels of the patients with AF were signficantly higher than those of the patients with no-AF(P<0.01). The higher plasma endothelin suggest that vasoconstriction is an important mechanism for hemodynamic compensation in EH patients with AF.
出处
《标记免疫分析与临床》
CAS
2000年第2期71-73,共3页
Labeled Immunoassays and Clinical Medicine
关键词
原发性高血压
内皮素
心钠素
心房颤动
Essential hypertension with auricular fibrillation Endothelin Natriuretic peptide, atrial
