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代谢综合征患者血清同型半胱氨酸与胱抑素C水平检测的临床意义 被引量:5

Clinical Significance of Detection of Homocysteine and Cystatin C in Patients with Metabolic Syndrome
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摘要 目的测定代谢综合征(MS)患者血清同型半胱氨酸(homocysteine,HCY)、胱抑素C(cystatin,CysC)的水平,探讨二者对代谢综合征患者的临床意义。方法随机收集代谢综合征患者血清30例,对照组血清32例。测定两组血清HCY、CysC的水平,并分析代谢综合征组HCY与CysC的相关性。结果代谢综合征组的血清HCY、CysC水平均较对照组升高且有统计学意义(P<0.05),并且代谢综合征组血清CysC与HCY呈正相关(r=0.652,P<0.01)。结论血清HCY和CysC水平均为可反映代谢综合征病情的较为敏感、准确、可靠的指标,两者联合检测对代谢综合征患者在诊断、治疗、病情监测上有一定的临床意义。 Objective To explore the clinical significance of sC) in patients with metabolic syndrome (MS). Methods serum homocysteine (HCY) and cystatin C (Cy- The plasma of levels of HCY and CysC in 30 pa- tients with MS and 32 normal controls were detected. The results were analyzed by SPSS17.0 software. Results The plasma levels of HCY and CysC in patients with MS were significantly higher than that of in normal con- trois (P 〈 0.05 ). The plasma levels of HCY in MS group were positive correlated with the plasma levels of Cy- sC ( r = 0.652, P 〈 0.01 ). Conclusion The plasma level of HCY and CysC both are sensitive, accurate and reliable indexes to reflect the patients' condition of MS. The combined detection of HCY and CysC may play an important role in the diagnosis, treatment and monitor the condition of patients with MS.
出处 《标记免疫分析与临床》 CAS 2012年第1期25-27,共3页 Labeled Immunoassays and Clinical Medicine
关键词 代谢综合征 同型半胱氨酸 胱抑素C Metabolic syndrome Homocysteine Cystatin C
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