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老年代谢综合征患者血浆同型半胱氨酸水平与血管内皮功能的研究 被引量:5

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摘要 目的探讨老年代谢综合征(MS)患者的血浆同型半胱氨酸(Hcy)水平及血管的内皮功能。方法选择老年MS患者40例(MS组)和健康查体者36例(NC组),检测血浆Hcy水平,同时应用超声检测内皮依赖性血管舒张功能(FMD)及硝酸甘油诱导的非内皮依赖性血管舒张功能(NID)。结果MS组Hcy〔(14.7±5.2)μmol/L〕明显高于NC组〔(10.2±3.1)μmol/L〕(P<0.01),FMD〔(6.7±2.1)%〕及NID〔(9.9±3.8)%〕低于NC组〔分别为(15.4±3.2)%,(15.6±4.1)%;P<0.05,P<0.01〕。FMD与年龄、BMI、TG、SBP、DBP、FBG呈负相关。结论老年MS患者血浆Hcy水平升高,血管内皮功能失调。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2006年第1期9-11,共3页 Chinese Journal of Gerontology
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  • 1Myers PR , A1-Swayeh OA , Chone NWS , et al. Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide [J]. Nature, 1990,345 :161-163.
  • 2Taddei S,Galetta F,Virdis A,et al. Physical activity prevents agerelated impairment in nitric oxide availability in elderly athletes[J]. Circulation, 2000 , 101 : 2896-2901.
  • 3Anderson TJ, Uehata A,Gerhard MD,et al. Close correlation of endothelial function in the human coronary and peripheral circulations[J]. J Am Coil Cardiol, 1995 , 26 : 1235-1241.
  • 4Yasue H,Matsuyama K ,Okumura K,et al. Responses of angiographically normal human coronary arteries to introcoronary injection of acetylcholine by age and segment :Possible role of early coronary at herosclerosis [J]. Circulation, 1990, 81 : 842-490.
  • 5Gerhard M ,Roddy MA ,Creager SJ ,et al. Aging progressively impairs endothelium-dependent vasodilatation in forearm resistance vessels of humans [J]. Hypertension, 1996,27:849-853.
  • 6Celermajer DS, Sorensen KE, Spiegelhalter DJ ,et al. Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women [J]. J Am Coil Cardiol, 1994,24:471-476.
  • 7Corretti MC,Plotnick GD,Vogel RA. Technical aspects of evaluating brachial artery vasodilation using high-frequency ultrasound [J]. Am J Physiol,1995,268:H1397-H1404.
  • 8Taddei S,Virdis A,Mattei P,et al. Hypertension causes premature aging of endothelial function in humans [J]. Hypertension, 1997,29 : 736-743.
  • 9Parthasarathy S,Barnett J,Fong LG. High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein [J].Biochem Biophys Acta,1990;1044:275-283.
  • 10Vogel RA, Corretti MC, Plotnick GD. Effect of a single high-fat meal on endothelial function in healthy subjects. Am J Cardlol, 1997,79:350-354.

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