摘要
目的：研究豫医无毛小鼠Ｈ 抗原系统的同源性。方法：采用近交培育２０ 代２ 月龄雌性豫医无毛小鼠皮肤异体移植法。结果：经１００ ｄ 观察，受试小鼠无急慢性排斥反应发生，移植皮片全部为永久性接受。结论：豫医无毛小鼠突变种群经２０ 代近交培育，组织相容性抗原一致。
Aim:To study the homology of H antigens in Yuyi hairless (YYHL)mice.Methods:Skin isografting was performed on inbred YYHL mice at age of 2 months.Result:There were no acute or chronic exclusions with the tested mice after being observed for 100 days.All the grafts were taken in permanently.Conclusion:The results suggest that the histocompatibility antigens are identical and the genes are provided with highly isogenicity in the mutant strain of YYHL mice after inbeding for 20 generations.
出处
《河南医科大学学报》
1999年第4期22-23,共2页
Journal of Henan Medical University
基金
河南省科技攻关资助项目
关键词
皮肤
异体移植
近交
H抗原
同源性
isografting
inbred
Yuyi Hairless Mice
H antigens
isogenicity
