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α-葡萄糖苷酶抑制剂的药理研究进展 被引量：13

The Development of Pharmacological Study of Alpha Glucosidase Inhibitor(AGI)
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摘要 α-葡萄糖苷酶是生命体正常运转的关键性酶,α-葡萄糖苷酶抑制剂可抑制α-葡萄糖苷酶的活性,阻断碳水化合物的分解、影响糖脂、糖蛋白生物合成中寡糖链的修剪。因此,α-葡萄糖苷酶抑制剂不仅可以调节体内糖代谢,还具有抗HIV和抗病毒感染的作用,对治疗和预防糖尿病及其并发症和控制艾滋病的传染等具有重要作用。 Alpha-Glucosidase is the key enzyme for the normal work of all living things,whose inhibitors can inhibit the activity of its enzyme,block the decomposition of Carbohydrate,and prevent the clipping of oligosaccharide-chains in the biological composition of glycolipid and gluco-protein.Thus,Alpha-Glucosidase inhibitors not only adept body＇s sugar-metabolism,but also functions as anti-HIV and anti-virus infections.Meantime,it is especially important for curing and preventing diabetes and their complications and controlling the infections of ADS and so on.
作者 郭风霞 曾阳 徐萌 杨琳
机构地区 青海师范大学生命地理科学学院 青海大学附属医院临床药学科 青海省第三人民医院临床药学科
出处 《青海师范大学学报（自然科学版）》 2011年第1期63-66,共4页 Journal of Qinghai Normal University(Natural Science Edition)
基金 青海省科技厅资助项目(No.2005-N-121) 青海师范大学中青年教师科研基金资助项目(No.2009-3-13)
关键词 Α-葡萄糖苷酶抑制剂 药理 研究进展 Aipha-Glucosidase inhibitor pharmacy development of study.
分类号 O59 [理学—应用物理]
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参考文献13

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  • 7刘霞,冯长根,等.酶抑制剂在抗糖尿病药物中的应用研究[J].中国药学杂志,2003,38(2):89-91. 被引量：32
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二级参考文献35

  • 1顾关云,蒋昱.植物降血糖成分的研究概况[J].国外医药（植物药分册）,1997,12(2):55-60. 被引量：21
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共引文献126

同被引文献164

引证文献13

二级引证文献145

青海师范大学学报（自然科学版）
2011年 第1期

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