摘要
目的了解该地区泌尿生殖道支原体感染及耐药情况,以指导临床合理用药。方法采用支原体培养、鉴定、药敏一体化试剂盒对该地区2 774例泌尿生殖道感染患者进行支原体培养及药敏试验。结果 2 774例患者中检出支原体阳性共1 248例(44.99%),其中单纯Uu感染1 231例(44.38%),单纯Mh感染2例(0.07%),Uu合并Mh感染15例(0.54%);支原体对药物的敏感性依次为美满霉素(MIN)89.75%、强力霉素(DOX)85.38%、克拉霉素(CLA)82.09%、交沙霉素(TOS)79.65%、四环素(TET)47.56%、左氧氟沙星(LEV)46.71%、司帕沙星(SPA)39.28%、阿奇霉素(AZI)35.08%、罗红霉素(ROX)28.1%、氧氟沙星(OFL)24.34%、红霉素(ERY)7.25%、诺氟沙星(NOR)5.14%。结论各地区支原体体外耐药谱差别较大,治疗需以药敏结果作为依据。该地区治疗泌尿生殖道支原体感染应首选美满霉素、强力霉素,红霉素、诺氟沙星耐药现象严重。
Objective To investgate the situation of urogenital Mycoplasma infection and drug resistance in genitourinary tract, so as to guide the rational medication. Methods Mycoplasma culture and drug resistance were tested for 2 774 patients with genito- urinary tract infection by one complex Kit including Myeoplasmars culture,identification and antibiotic susceptibility. Results 1 248 cases were infected with Mycoplasma in 2 774 tested patients, the positive rate was 44. 99%, among which, M. urealyticum（Uu） were 1 231 cases（44.38%）,M, hominis（Mh） were 2 cases（0.07 %）,Uu combined with Mh were 15 cases（0.54%）. The sensitive drugs for Mycoplas.ma were minocycline（89.75 % ）, doxycycllne（ 85.38 % ）, clarithromyein（ 82.29% ）, josamycin（ 79.65% ）, tetracy cline（47.56 %）, levofloxacin （ 46. 71 % ）, sparfloxacin （ 39. 28%）, azithromycin （ 35. 08%, roxithromycin （ 28. 1%）, ofloxacin （ 24. 34%） ,erythromycin（7.25%）and norfloxacin（5.14%） ,recpectively. Conclusion The difference of Mycoplasma＇s drug resistance is large in different areas,so the treatment should depend on the results of sceptibility test. In our areas, application of rninocycline, doxycycline in priority to cure Mycoplasma in genitourinary tract infection. The resistarice phenomena is serious in erythromycin and norfloxacin.
出处
《国际检验医学杂志》
CAS
2011年第2期205-206,共2页
International Journal of Laboratory Medicine
关键词
解脲支原体
支原体
人型
微生物敏感性试验
ureaplaSma urealytieum
mycoplasma hominis
. microbial sensitivity tests
