摘要
目的了解粤北地区非淋菌性尿道炎(NGU)中支原体感染的情况及对药物敏感性的现况。方法对3 280例NGU患者的分泌物、前列腺液等进行支原体培养鉴定、计数及药敏试验。结果3 280例中支原体阳性1 221例,感染率为37.22%;Uu、Mh及Uu+Mh混合感染的阳性率分别为28.11%(922例)、2.77%(91例)、6.34%(208例);Uu对12种抗菌药物敏感性最高的是交沙霉素(92.96%)、左氧氟沙星(88.21%),其次是司帕沙星(83.62%);耐药性最高的是环丙沙星(29.24%),其次红霉素(35.14%)、多西环素(42.83%)。结论粤北地区支原体对环丙沙星、红霉素、多西环素的耐药性较高,对米诺环素、克拉霉素的耐药性也呈上升趋势;对于NGU患者原则上应当进行培养加药敏试验,指导临床治疗,最大限度地控制新耐药菌株的发生。
OBJECTIVE To understand the situation of Mycoplasma infection and drug sensitivity in the patients of nongonococcal urethritis（NGU） in area of Yuebei. METHODS Totally 3 280 specimens in the patients of NGU were collected, cultured and tested for drug sensitivity. RESULTS From them there were 1 221 patients who had Mycoplasma（37.22%）. The simple infection of Ureaplasma urealyticun （Uu） was 922 cases （28. 11%） and Mycoplasma（Mh） 91 cases （2.77%）, respectively. The mixed was 208 cases（6.34%）. The result of drug sensitivity showed that sensitivity of Mycoplasma to josamycin was the highest, then was to levofloxacin （Cravit） and sparfloxacin. Ciprofloxacin was with the highest drug resistance, then were erythromycin and doxycycline. CONCLUSIONS Mycoplasma have high drug resistance to ciprofloxacin, erythromycin and doxycycline. The resistance rate to minocycline and clarithromycin is in a rising tendency. The antibiotics should be used reasonably to reduce the development of drug-resistant strains.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2006年第2期235-237,共3页
Chinese Journal of Nosocomiology
关键词
非淋菌性
支原体感染
解脲脲支原体
人支原体
药敏
耐药性
Mycoplasma infection
Ureaplasma urealyticun
Mycoplasma hominis
Drug sensitivity
Drug resistance
