摘要
目的了解某地区泌尿生殖道支原体感染及其对9种抗菌剂药敏的情况,为临床合理用药提供依据。方法采用支原体培养、鉴定、药敏一体化试剂盒对2327例患者标本进行支原体培养及药敏实验,并用SPSS软件对结果进行统计分析。结果 2327例标本中检出支原体阳性1016例,总阳性率为43.7%,其中Uu、Mh及Uu+Mh的阳性率分别为37.4%、1.0%、5.2%。支原体对9种抗菌剂总的药物敏感性分别为:MIN(92.2%)、DOX(91.3%)、JOS(84.4%)、CLA(80.5%)、AZI(60.5%)、ROX(42.0%)、SPA(39.2%)、LEV(27.3%)、OFL(15.6%)。在支原体阳性标本中,呈三种或三种以上抗菌剂耐药的支原体占23.1%。结论某地区支原体感染率较高,主要以Uu为主,Mh及Uu+Mh的感染也不容忽视。临床应根据药敏实验结果合理使用抗菌剂,以控制耐药率的进一步上升,提高疗效。某地区治疗支原体首选药物为MIN和DOX。
Objective To understand the status of mycoplasma infection in genitourinary tract and drug susceptibility to 9 antibiotics to provide basis for rationally clinical usage of drugs.Methods Culturing and drug susceptibility of mycoplasma were tested for 2 327 patients with genitourinary tract infection by one complex kit including culture,identification and antibiotic susceptibility.The results were analyzed by SPSS software.Results 1 016 cases were infected with mycoplasma in 2 327 tested patients,with total positive rate of 43.7%.The positive rates of Uu,Mh and Uu＋Mh were respectively 37.4%,1.0% and 5.2%.The susceptibility of mycoplasma to 9 antibiotics was MIN（92.2%）,DOX（91.3%）,JOS（84.4%）,CLA（80.5%）,AZI（60.5%）,ROX（42.0%）,SPA（39.2%）,LEV（27.3%） and OFL（15.6%）.Conclusion Mycoplasma infection rate was high in this area,mainly by Uu,but Mh and Uu＋Mh infection could also exist.Antibiotics should be reasonably used according to the medicine sensitive test results to control the further increasing of resistance rate and enhance the curative effect.MIN and DOX could be the first choice for the treatment of mycoplasma infection in this area.
出处
《国际检验医学杂志》
CAS
2012年第13期1615-1617,共3页
International Journal of Laboratory Medicine
关键词
支原体
泌尿生殖道
耐药性
Mycoplasma； genitourinary； drug resistance
