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水通道蛋白与肺水肿相关性研究进展 被引量:4

Study progress of correlation between aquaporin and pulmonary edema
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摘要 水通道蛋白对调节肺组织中水的转运起着重要作用,研究发现多种原因导致的肺水肿都有水通道蛋白表达数量的改变.通过改变水通道蛋白的表达数量,增强肺水肿患者的肺泡清除率,减轻肺水肿,可能是治疗肺水肿的有效新途径. Aquaporin plays an important role in regulating water transport in lung. Researches have found that the expression of aquaporin changes in pulmonary edema induced by many reasons. By changing the expression of aquaporin, alveolar clearance rate of patients with pulmonary edema increases, pulmonary edema relieves, which may be a new and effective therapy for pulmonary edema.
出处 《国际呼吸杂志》 2010年第12期753-756,共4页 International Journal of Respiration
基金 军队“十一五”攻关项目(08G-102)
关键词 水通道蛋白 肺水肿 Aquaporin Pulmonary edema
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  • 1谢艳萍,陈才平,王建春,钱桂生,王应灯,肖贞良.急性肺损伤大鼠肺水通道蛋白1和5的表达及功能的实验研究[J].中华结核和呼吸杂志,2005,28(6):385-389. 被引量:37
  • 2靳国恩,张伟,杨应忠,杨全余,周晓梅,多杰,格日力.十五味沉香散等5种藏药抗慢性缺氧的实验研究[J].中草药,2007,38(1):95-97. 被引量:15
  • 3急性肺损伤/急性呼吸窘迫综合征诊断与治疗指南(2006)[J].中华内科杂志,2007,46(5):430-435. 被引量:254
  • 4Ruiz-Ederra J, Verkman AS. Acrelerated calaract for mation and reduced lens epithelial water permeaility in aquaporin-1 deficient mice. Invesl ophthalmol Vis Sci ,2006, 47:3960-3967.
  • 5Pedersen PS, Braunstein TH, Jorgensen A, et al. Stimulation of apuaporin-5 and transepithelial water permeability in human airway epithelium by hyperosmotic stress. Pfugers Arch, 2007, 453:777- 785.
  • 6Verkman AS. Role of aquaporins in lung liquid physiology. Respir Physiol Neurobiol, 2007, 159:324-330.
  • 7Smith KM, Mrozek JD, Simonton SC, et al. Prolonged partial liquid ventilation using conven-tional and high-frequeney ventilatory techniques: gas exchange and lung pathology in an animal model of respiratory distress syndrome. Crit Care Med, 1997, 25:1888-1897.
  • 8Preston GM, Agre P. Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family. Proc Natl Aead Sei U S A,1991,88: 11110-11114.
  • 9King LS, Yasui M, Agre P. Aquaporins in health and disease. Mol Med Today, 2000,6 : 60-65.
  • 10Bai C, Fukuda N, Song Y, et al. Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice. J Clin Invest, 1999,103:555-561.

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