摘要
目的建立克感平滴丸的质量标准。方法采用TLC定性鉴别克感平滴丸中的满山红、北豆根,采用RP-HPLC定量检测杜鹃素的含量。结果在TLC中分别检出满山红、北豆根,斑点清晰可见,重现性好。利用RP-HPLC得到的杜鹃素的线性范围为0.125～2.0μg,r=0.9999;杜鹃素的平均回收率为99.6%,RSD=0.43%(n=6)。结论定性定量方法简便、专属、准确,能有效的控制克感平滴丸的质量。
OBJECTIVE To establish the quality specification of compound Keganping dripping pills.METHODS TLC was used to identify folium rhododendri daurici and rhizoma menispermi radix in compound Keganping dripping pills.RP-HPLC was used to determine the content of farrerol.RESULTS Folium rhododendri daurici and rhizoma menispermi radix in compound Keganping dripping pills was found on TLC.The spot was clear.The method showed a good reproducibility.The linear range of farrerol was in the range of 0.125-2.0 μg（r=0.999 9）.The farrerol average recovery rate was 99.6% with RSD of 0.43%（n=6）.CONCLUSION The method is simple,efficient,sensitive and can be applied to quality control of compound Keganpin dripping pills.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2010年第5期385-387,共3页
Chinese Pharmaceutical Journal
基金
哈尔滨市科技局科技创新人才研究专项资助项目(2009RFXXS212)
