摘要
采用荧光法测定了4位健康受试者尿液中的原形药物量。尿样不须先经处理,当主药浓度在0.05~0.5μg/ml范围内,其荧光强度与浓度线性关系良好。
A fluorescence spectrophotometry was developed for the determination of original drug content of norfloxacin in urine, and the biological halflife was calculated by the excretion rate to be 5 h. The calibration curve was linear in the concentration range of 0.05 ̄0.5 μg/ml.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1998年第8期359-361,共3页
Chinese Journal of Pharmaceuticals
关键词
诺氟沙星
荧光分光光度法
生物半衰期
尿药排泄速率
norfloxacin, biological halflife, excretion rate, fluorescence spectrophotometry