摘要
对１１０例膀胱癌住院病例进行了病例对照研究。结果显示吸烟者有显著升高的膀胱癌危险度（ＯＲ＝２．１３，９５％ＣＩ为１．１８～３．８４），尤其吸烟年限在４０年以上者，其危险度高达４．１０倍。开始吸烟年龄越小危险性越大，并随着吸烟年限、吸烟量、吸烟深度的增加而增加，随戒烟年限的增加而减小，呈明显的剂量－反应关系。经年龄调整后，吸烟致膀胱癌的人群归因危险度为４２％。吸烟与危险职业暴露对膀胱癌的发生有交互作用，其相对超额危险度为４．６８。
A casecontrol study on 110 bladder cancer inpatientswas conducted.The results showed that cigarette smoking was an important risk factor for bladder cancer.The odds ratio(OR)and 95% confidence interval(95%CI) of having bladoer cancer for cigarette smoking was 2 13(1 18～3 84).when smoking time was more than 40 years,the odds ratio was 4 1. The younger start smoking age,the larger risk.The strength of risk increased with the amount smoked and length smoked.It decreaded with increasing of smoking quitting years.There are doserespones relationship between amount smoked and risk.After age adjustment,the population attributable risk(PAR)of bladder cancer due to smoking was 42%.In the process that bladder cancer come on,the interactive effect between cigarette smoking and risk occupation exposure was existed,the relative excess risk was 4 68.
关键词
膀胱癌
吸烟
危险职业
交互作用
Bladder cancer Cigarette smoking Risk occupation Interactive effect
