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隐函数Delta法调整人群归因危险度可信区间的估计及其应用 被引量:2

Estimating the Confidence Intervals of the Adjusted Population Attributable Risk (PAR) and its Application through the Implicit Delta Method
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摘要 目的 介绍隐函数Delta法计算调整人群归因危险度 (PAR)可信区间的基本原理和SAS编程方法。方法 实例介绍用SASPROCIML过程 ,实现病例 -对照研究中调整PAR及其可信区间的估计。结果 利用此程序计算了上海市男性食管癌病例 -对照研究资料吸烟、饮酒和水果摄入过少因素的调整PAR及其 95 %可信区间分别为 46 5 9%( 3 4 92 %~ 5 8 2 6%) ,2 0 87%( 10 2 8%~ 3 1 47%)和 3 4 5 4%( 19 81%~ 49 2 9%)。结论 对符合条件的病例 -对照资料 。 Objective The paper introduced basic idea of estimating the confidence intervals of the adjusted population attributable risk based on the implicit delta method and sas program. Methods Using the example illustrated how to write the program with the proc iml procedure in sas environment to carry out the estimation of the adjusted PAR and confidence intervals with the case-control data. Results The adjusted PAR and 95% confidence intervals for the cigarette smoking, alcohol drinking and less fresh fruits intake attributed to the esophageal cancer among the male in Shanghai urban city were calculated as 46.59%(34.92%~58.26%), 20.87%(10.28%~31.47%) and 34.54%(19.81%~49.29%), respectively.Conclusion Through the implicit delta method, the accurate estimation of the PAR and confidence intervals were more likely to acquire provided the case control data satisfied the corresponding condition. It has the practical significance for the method to the prevention from the chronic disease.
出处 《中国卫生统计》 CSCD 北大核心 2004年第3期142-145,共4页 Chinese Journal of Health Statistics
关键词 隐函数Delta法 人群归因危险度 可信区间 PAR 回归模型 Implicit delta method, Adjusted population attributable risk, Confidence intervals estimation
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  • 1Benichou J, Gail M H. Variance calculation and confidence intervals for estimates of the attributable risk based on logistic models. Biometrics 1990, 46: 991.
  • 2Bruzzi P, Green SB, Byar DP, et al. Estimating the population attributable risk factors using case-control data. Am J Epdemiol, 1985,122(5) :904.
  • 3Benichou J, Gail MH. A delta-method for implicitly defined random variables. Am Statistician, 1989, 42(1): 41.
  • 4Mezzetti M, Ferraroni M, Decarli A. Software for attributable risk and confidence interval estimation in case-control studies. Comput Biomed Res, 1996, 29 (1): 63.
  • 5Gao Yu-Tang, McLaughlin JK, Bolt WJ, et al. Risk factors for esophageal cancer in Shanghai, China. I. Role of cigarette smoking and alcohol drinking. Iht J Cancer, 1994, 58:192.
  • 6Llorca J, Delgado-Rodriguez M. A comparison of several procedures to estimate the confidence interval for attributable risk in case-control studies.Stat Med, 2000, 19(8): 1089.
  • 7王天爵.病例对照研究资料调整人群归因危险度的估计[J].中国卫生统计,1992,9(1):60-62. 被引量:6

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