摘要
脑缺血再灌注后脑组织局部过度炎性反应是导致新生儿缺氧缺血性脑病(HIE)、脑损伤的主要机制之一,临床上检测患儿血清及脑脊液中与HIE相关的细胞因子,对新生儿HIE病情的早期评估、疗效及远期预后的评价具有重要的价值,而细胞因子的免疫学治疗尚有待进一步研究。
Excessive inflammatory reaction in local brain tissue resulting from cerebral ischemia and reperfusion is one of the main mechanism resulting in HIE and brain injury. Detection of some cy tokines related to HLE in serum and cerebrospinal fluid of patients has great significance on pathogenetic conditions of newborn with HIE about its early evaluation, therapeutic effect and evaluation of future prognosis,While immunotherapy with cytokines still needs further studying.
出处
《医学综述》
2007年第16期1215-1217,共3页
Medical Recapitulate
关键词
新生儿
脑缺血
脑缺氧
细胞因子
Newborn
Cerebral ischemia
Cerebral anoxia
Cytokine
