摘要
目的：对中药南方菟丝子（Ｃｕｓｃｕｔａａｕｓｔｒａｌｉｓ）的种子中化学成分进行分离、鉴定研究。方法：采用溶剂分离法结合柱色谱法进行成分分离。所得成分再分别采用５种色谱：ＵＶ、ＩＲ、１ＨＮＭＲ、１３ＣＮＭＲ和ＭＳ测定其结构。结果：从南方菟丝子的种子中分离得到６种成分，经光谱鉴定分别为紫云英苷（ａｓｔｒａｇａｌｉｎ，Ⅰ）、β谷甾醇（βｓｉｔｏｓｔｅｒｏｌ，Ⅱ）、虫漆醋酸（ｌａｃｃｅｒｏｉｃａｃｉｄ，Ⅲ）、β谷甾醇３ＯβＤ吡喃木糖苷（βｓｉｔｏｓｔｅｒｏｌ３ＯβＤｘｙｌｏｐｙｒａｎｏｓｉｄｅ，Ⅳ）、山萘酚（ｋａｅｍｐｆｅｒｏｌ，Ⅴ）、槲皮素（ｑｕｅｒｃｅｔｉｎ，Ⅵ）。结论：化合物Ⅳ为新化合物；除化合物Ⅱ以外，其余化合物均为首次从该植物中发现。
OBJECTIVE:To investigate the chemical constituents from the seeds of Cuscuta australis,from which about 90% commercial dodder was derived.METHODS:To isolate the flavonoides and sitosterol derivants,the solvent extraction together with the column,chromatography and TLC methods were used.Several spectral methods such as IR,UV, 1H NMR, 13 C NMR and MS were used to determine the structure of the isolated constituents.RESULTS:In six constituents obtained,three were flavonoids,astragalin(Ⅰ),kaempferol(Ⅴ) and quercetin(Ⅵ),two were β sitosterol(Ⅱ) and β sitosterol 3 O β D xylopyranoside(Ⅳ),one novel compound,and the other one was lacceroic acid(Ⅲ).CONCLUSION:In this plant these compounds except β sitosterol have not been discovered previously.
出处
《中国药学杂志》
CAS
CSCD
北大核心
1997年第1期8-11,共4页
Chinese Pharmaceutical Journal
关键词
南方菟丝子
Β-谷甾醇
吡喃木糖苷
化学成分
Cuscuta australis,β sitosterol 3 O β D xylopyranosides,astragalin,kaempferol,quercetin,lacceroic acid
