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绞股蓝微乳的研制及其质量评价 被引量:4

Preparation of Gynostemma Pentaphyllum Microemulsion and its Quality Evaluation
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摘要 采用伪三元相图法进行处方优选,并初步考察了微乳制剂的稳定性及其理化性质。结果表明,以蓖麻油聚氧乙烯醚40(RH40)为表面活性剂,1,3-丁二醇作为助表面活性剂和肉豆蔻酸异丙酯(IPM)为油相加入绞股蓝后形成微乳系统;绞股蓝微乳稳定,透射电镜下呈圆球形,分布均匀,平均粒径在40 nm左右。绞股蓝微乳制备简单,性质稳定。 In the paper, the formulations of the gynostemma pentaphyllum microemalsion were optimized by studying the pseudotertiary phase diagram and the stability and quality of gynostemma pentaphyllum microemulsion were tested. The results were as follows: in the microemulsion of RH-40/IPM/1, 3-butanediol system, gynostemma pentaphyllum microemulsion was very stable after three months storage. Gynostemma pentaphyllum microemulsion in electron microscopy were small spherical drops with a mean diameter of 40 ran. Gynostemma pentaphyllum microemulsion is easy to prepare.
出处 《安徽农业科学》 CAS 北大核心 2007年第4期1051-1052,1112,共3页 Journal of Anhui Agricultural Sciences
基金 西北农林科技大学校长专项基金(130709)
关键词 绞股蓝 微乳 伪三元相图 质量评价 Gynostemma pentaphyllum Microemalsion Predutemy phase disgram Quality evaluation
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  • 1吴顺芹,李三鸣,郎轶咏,刘华,刘洪卓.水包油型微乳形成因素的考察[J].沈阳药科大学学报,2005,22(2):96-99. 被引量:21
  • 2李干佐,郝京诚,李方,刘尚营,汪汉卿.阳离子表面活性剂中相微乳液的形成和特性[J].物理化学学报,1995,11(6):553-557. 被引量:16
  • 3王倩,丁红梅,周海源.微乳相图及工艺研究[J].西北药学杂志,1997,12(2):72-73. 被引量:21
  • 4SFDA.Guidance for the irritation,hepersensitivity and hemolytic testing of generic chemical medicine(化学药物刺激性、过敏性和溶血性研究技术指导原则)[EB/OL].http://www.sda.gov.cn/gsz05106/14.pdf.2005-03-18.
  • 5RADOMSKA A,DOKRUCKI R.The use of some ingredients for microemulsion preparation containing retinal and its esters[J].Int J Pharm,2000,196(2):131-134.
  • 6VANDAMME T H F.Microemulsions as ocular drug delivery systems:recent developments and future challenges[J].Prog Retin Eye Res,2002,21 (1):15-34.
  • 7LUB.New Tecniques and New Dosage Forms of Drugs(药物新剂型与新技术)[M].Beijing:People' s Medical Publishing House,1998:93-94.
  • 8HASSE A,KEIPERT S.Development and characterization of microemulsions for ocular application[J].Eur J Pharm Biopharm,1997,43 (2):179-183.
  • 9SHAUL M,MUHAMAD A,JOSEPH F,et al.Ex-vivo permeation study of indomethacin from a submicron emulsion through albino rabbit cornea[J].J Controlled Release,1997,44(1):55-64.
  • 10郭荣,宋根萍,于卫里.维生素C在CTAB/n-C_5H_(11)OH/H_2O体系中的增稳作用[J].高等学校化学学报,1997,18(4):600-604. 被引量:11

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