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血浆TU M_2-PK检测对肺癌的诊断价值 被引量:6

Plasma tumor M_(2) pyruvate kinase detection in diagnosis of lung cancer
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摘要 目的:评价血浆肿瘤M2型丙酮酸激酶(TU M2-PK)对肺癌的诊断价值。方法:应用夹心ELISA法检测64例肺癌患者、50例良性肺病患者及42名健康人血浆TU M2-PK的含量并加以比较。对肺癌患者进行TNM分期,比较不同分期的TU M2-PK水平。结果:肺癌患者血浆TU M2-PK水平显著高于良性肺病患者及健康人(P<0.01),且TNM分期越晚,其水平越高(P<0.01)。良性肺病患者与健康人血浆TU M2-PK水平差异无统计学意义。血浆TU M2-PK检测肺癌的敏感性为89.1%,特异性为94.0%。结论:血浆TU M2-PK可作为肺癌的一个较好的诊断标志物,测定其在血浆中的浓度变化,对肺癌患者的早期诊断和病情判断均有重要意义。
出处 《第二军医大学学报》 CAS CSCD 北大核心 2006年第2期219-220,共2页 Academic Journal of Second Military Medical University
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