期刊文献+

孕妇血清PAPP-A和VCAM-1水平与妊娠期高血压疾病的关系 被引量:6

暂未订购
导出
摘要 目的:探讨PAPP-A和VCAM-1在妊娠期高血压疾病发病中的作用。方法:采用酶联免疫吸附法测60例正常孕妇和60例妊娠期高血压疾病孕妇(其中妊娠期高血压30例,子痫前期20例,子痫10例)血清中PAPP-A和VCAM-1水平。结果:子痫前期、子痫患者PAPP-A和VCAM-1水平显著高于对照组(P<0.01),子痫前期、子痫患者PAPP-A和VCAM-1有显著相关性(r=0.83)。结论:PAPP-A和VCAM-1在妊娠期高血压疾病发病中起重要作用。
作者 李春芳 方静
出处 《实用医学杂志》 CAS 2005年第10期1032-1033,共2页 The Journal of Practical Medicine
  • 相关文献

参考文献6

  • 1Bersinger NA,Groome N,Mut Tukrishna S.Pregnancy associated and placental proteins in the placental tissue of normal pregnant women and patients with preeclampsia at term.Eur J Endocrinol,2002,147(6): 785- 793.
  • 2Bersinger NA,Smarason AK,Mut Tukrishna S,et al.Women with preeclampsia have increased serum levels of pregnancy associated plasma protein A(PAPP-A), inhibin A,activin A and soluble E2 selectin.Hypertens Pregnancy,2003,22(1): 45- 55.
  • 3Wilczynski JR,Glowacka E,Nowak M,et al.Serum concentration of soluble vascular-cellular adhesion molecule-1(VCAM-1)and expression of its receptor VLA-4 on the surface of peripheral blood and decidual lymphocytes of preeclamptic women. Ginekol Pol,2003,74(10): 1335- 1342.
  • 4Hey LW.The role of soluble adhesion molecules in evaluating chdothelial cell activation in preeclampsia.Am J Obstet Gynecol,1999,180(1 pt 1): 68- 72.
  • 5Stein A.Labor-associated expression of intercellulas adhesion molecule-1 in placental endothelial cells indicates participation of immunological process in parturition.Placenta,1999,20(7): 567- 573.
  • 6林其德.子癎前期子癎病因及发病机制的研究进展[J].中国实用妇科与产科杂志,2004,20(10):577-579. 被引量:70

二级参考文献3

  • 1Genbacev O,Zhou Y,Ludlow JW,et al.Regulation of human placental development by oxygen tension.Science,1997,277(5332):1669-1672
  • 2Barber A,Robson SC,Myatt L,et al.Heme oxygenase expression in human placenta and placental bed:reduced expression of placenta endothelial HO-2 in preeclampsia and fetal growth restriction.FASEB J,2001,15(7):1158-1168
  • 3Many A,Hubel CA,Fisher SJ,et al.Invasive cytotrophoblasts manifest evidence of oxidative stress in preeclampsia.Am J Pathol,2000,156(1):321-331

共引文献69

同被引文献59

引证文献6

二级引证文献40

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部