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生殖细胞凋亡与男性不育症 被引量:7

Apoptosis of reproductive cells and male infertility
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摘要 近年对细胞凋亡的认识逐渐深入,已经开始在生殖健康领域应用。已证实在自然状态和正常生精过程中,环境因素如激素、温度、化学药物和放射线及肿瘤均可诱导生殖细胞凋亡。生精细胞凋亡受神经内分泌因素、各种理化因素、特异性基因及基因突变等许多因素的影响。根据凋亡细胞固有的形态特征,人们已经设计了许多不同的细胞凋亡形态学检测方法。 In the recent years, the knowledge on cell apoptosis has been deepened increasingly, and accordingly be-gan to be applied to the field of reproductive health. It has been confirmed that in the natural status and normal spermatogenic course, environmental factors such as hormones, temperature, chemicals, radioactive rays, and tumors may induce apoptosis of reproductive cells. The apoptosis of spermatogenic cells is influenced by multiple factors, such as neuroendocrine, physical and chemical factors, specific genes, and gene mutations. According to the morphological method for detection of many different apoptoctic cells has been developed.
机构地区 中日友好医院
出处 《中国性科学》 2004年第6期3-7,共5页 Chinese Journal of Human Sexuality
关键词 生殖细胞 男性 不育症 细胞凋亡 生精细胞 烷基酚 环境污染 Reproductive cells Cells apoptosis Male infertility
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  • 1徐晨.沙眼衣原体与不育不孕[J].男性学杂志,1994,8(3):180-184. 被引量:31
  • 2汪宁,赵季文,徐萃瑜,贺晓新,林舜华,方海林,姚航平.不同人群生殖泌尿道解脲支原体1~14血清型感染状态的研究[J].中华流行病学杂志,1995,16(4):207-210. 被引量:32
  • 3杨建华,孙广芳,徐晨,王一飞.溶脲脲原体感染与精子顶体反应[J].生殖与避孕,1995,15(3):210-213. 被引量:11
  • 4[1]Chang PL,Sauer MV,Brown S.Y chromosome microdeleiton in a father and his four infertile sons[J].Hum Reprod,1999,14(11):2689~2694.
  • 5[2]Cooke HJ,Hargreave T,Elliott DJ.Understanding the genes involved spermatogenesis:aprogress report.Fertil Steril,1988,69:989~995.
  • 6[6]Tiepolo L,Zuffardi O.Localization of factors controlling spermato-genesis in the non-fluorescent portion of the human Ychromosome long arm[J].Hum Genet,1976,34(2):119.
  • 7Saypol DC, Howavds SS, Turnex TF, et al. Influence of surgically induced varicocele on testicular blood flow, temperature, and histology in adult rats and dogs[J]. J Clin Invest, 1981,68(1):39.45.
  • 8Billig H, Furuta I, Rivier C, et al. Apcptcsis in the testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages[J], Endocrinology, 1995, 136(1) :5-12.
  • 9Hsueh M, Eisenhauer K, Chun SY. Gonadal cell apoptosis[J]. Recent Prog Horm Res, 1996, 51 ( 1 ) :455-456.
  • 10Moil C, Nakamura N, Dix DJ, et al. Morphological analysis of germ cell apoptosis during postnatal testis development in normal and HSPT0-2 knockout mice[J], Dev Dyn, 1997, 208( 1 ) :125-136.

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