摘要
本研究用免疫细胞化学方法(ABC法)观察了降钙素基因相关肽(CGRP)在SD大鼠肺中的分布,缺氧对肺中神经内分泌细胞内CGRP含餐的影响。结果表明:含CGRP的神经纤维分布在肺血管平滑肌层中及其周围、气管-支气管树的粘膜下层;含CGRP的神经内分泌细胞位于气管一支气管树的上皮层、粘液腺中和肺实质内。缺氧不引起火鼠肺的神经内分泌细胞数目改变,但可使这些细胞内的CGRP含量增加。
We observed the distribution of calcitonin gene-related peptide in the SD rat lung and the effect of hypoxia on its quantity by means of immuno-cytochemistry (ABC method). The results show that the CGRP-containing nerve fibers were distributed among smooth muscle, around blood vessels; beneath the epithelium of the trachea-bronchial trees. CGRP-containing endocrine cells were localized within the epithelium of trachea-bronchial trees, in the seromucous glands, and in the lung parenchyma. Hypoxia did not change the number of endocrine cells, but increased the intracellular levels of CGRP.
出处
《同济医科大学学报》
CAS
CSCD
北大核心
1992年第5期299-301,359,共4页
Acta Universitatis Medicinae Tongji
关键词
降钙素
基因相关肽
肺
calcitonin gene-related peptide
lung
neurocndocrine cell
hypoxia
