摘要
本文用自旋捕捉电子自旋共振实验方法,证实大蒜及其水溶性提取物含硒蛋白和含硒多糖对羟自由基((?)OH)和超氧阴离子自由基((?))等活性氧自由基有较强的清除能力。可以与常用的自由基清除剂 SeO_3^(2-)和 VC 相比拟。提示大蒜清除活性氧自由基是其重要的药理作用之一。文中还对其清除机制进行了初步探讨。
By means of spin trapping-electron spin reso-nance method,the active oxyradical scavenging ef-fects of garlic juices and the water soluble Se-pro-tein and Se-polysaceharides extracted from garlicwere studied in hydroxyl radical(·OH)and super-oxide anion((?))generating systems.The results in-dicate that the garlic juices scavenge · OH and (?)effectively,while the scavenging effect of Se-polysaccharide is lower than that of Se-protein.Nevertheless,the scavenging effects of garlic isshown to be comparable to Vc and Seo_3^(2-).It isshown that the pharmacologic activity of garlic isrelated to its active oxyradical scavenging effects.
出处
《中国药学杂志》
CAS
CSCD
北大核心
1992年第6期339-342,共4页
Chinese Pharmaceutical Journal
关键词
大蒜
提取物
ESR
garlic
water soluble extractor
spin trapping
electron spin resonance
scavenger of radicals
