摘要
目的:探讨2型糖尿病患者抑郁情绪表现及其对疗效的影响,寻求进行干预的可能性。方法:87例2型糖尿病患者(糖尿病组)按相同年龄、性别、民族,文化程度和婚姻状况与正常人(对照组)进行1:1配对,在治疗前后用汉密顿抑郁量表(hamiltionratingscalefordepression,HAMD)进行测评。结果:糖尿病组中有抑郁情绪患者31例(36.5%),平均HAMD得分为18.4±5.7,明显高于对照组(7例,8.0%和9.6±2.5)(χ2=19.393,P<0.001和t=2.443,P<0.05)。31例有抑郁情绪患者中显效和有效例数20例,总有效率64.5%,56例无抑郁情绪患者中显效和有效例数53例,总效率94.6%,后者疗效明显优于前者(χ2=13.413,P<0.001)。2型糖尿病疗效显著患者的HAMD分项评分中的焦虑躯体化(2.09±0.45),认知障碍(1.24±0.27),昼夜变化(0.83±0.10),迟缓(4.75±1.330,睡眠障碍(2.29±0.053)和绝望感(2.62±0.60),均明显低于无效患者(t=2.075～2.225,P均<0.05),而有效患者中的焦虑、躯体化、迟缓和绝望感显著低于无效患者(t=2.149～2.256,P均<0.05)。结论:2型糖尿病患者有较高的抑郁情绪患病率,后者对疗效有明显影响。
AIM:To study depression emotional expression and curative effect in type 2 diabetic patients,and to explore the possibility of rehabilitation intervention. METHODS:Eighty seven type 2 diabetic patients(diabetic group) were matched with normal subjects(control group)by the same age, sex,nationality,civilization level and marriage status.The two groups were evaluated with Hamilton rating scale for depression(HAMD) before and after treatment. RESULTS:The incidence rate of depression and mean values of HAMD[36.5% (31 cases),18.4± 5.7]in the diabetic group were obviously higher than those in the control group[8.0% (7 cases),9.6± 2.5](χ 2=19.393, P< 0.001 and t=2.443,P< 0.05).In the diabetic group,20(64.5% ) of the 31 patients with depressive emotion were obviously effective and effective,53(94.6% ) of the 56 patients without depressive emotion were obviously effective and effective, and the effect of the former was obviously better than that of the latter(χ 2=13.413,P< 0.001).The scores of HAMD such as anxiety and somatization(2.09± 0.45),cognitive handicap(1.24± 0.27),transformation of day and night(0.83± 0.10),retardation(4.75± 1.330),sleep disorder(2.29± 0.053) and the feeling of despair(2.62± 0.60) in diabetic patients with obvious effect were obviously lower than those without effect(t=2.075- 2.225,all P < 0.05),while the anxiety, somatization, retardation and feeling of despair in those with effect were significantly lower than those without effect(t=2.149- 2.256,all P< 0.05). CONCLUSION: It is suggested that the prevalence rate of depression is very high in type 2 diabetic patients,and the results have obvious effect on the curative effect.
出处
《中国临床康复》
CSCD
2004年第6期1008-1009,共2页
Chinese Journal of Clinical Rehabilitation
