摘要
目的 :调查重症监护病房 (ICU )应用人工气道进行机械通气的患者伴呼吸机相关性肺炎的致病菌群及药敏情况。方法 :对 10 9例建立人工气道的机械通气伴呼吸机相关性肺炎的患者痰培养分离出的 187株致病菌进行药敏试验。结果 :革兰阳性菌占 8.0 %。革兰阴性菌占 79.7% ,分别列前 3位的是铜绿假单胞菌 (2 6.8% )、不动杆菌属 (18.8% )、克雷伯杆菌属 (14 .1% )。药敏结果表明 :所有革兰阴性菌对抗菌药物的耐药率呈上升趋势。结论 :呼吸机相关性肺炎的病原菌仍以革兰阴性菌为主 ,不动杆菌属、真菌检出率较高。为避免耐药率的升高 。
Objective: To investigate the distributiona nd sensitivity of pathogenic bacteria in ventilator-associated pneumonia (VAP). Methods: In109 patients ,187 strains of pathogens in ventila tor-associated pneumonia wereclassified and drug resistance was analyzed. Results:Fifteen of 187 strains were gram-positive bacilli (8.0%),149 of 187 strains were gram-negative bacilli (79.7%) ,and 23 of187 strainswere fungi (12.3%).The predominant pathogens were pseudomonas aeruginosa (26.8% ),acinetobacter baumanii(18.8%) ,and klebsiella pneumoniae(14.1%).Drugsensit ivity test showed that the drug resistance rate was in an increasing tendency ingram-negative bacilli. Conclusion: The gram-negative bacill i are the main pathogens in ventilator-associated pneumonia .The incidence of i nfection with acinetobacter baumaniiand fungi are increasing. In order to cont rol the drugresistance,reasonable application of antibiotics should beemphasi zed.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2004年第1期53-55,共3页
Journal of China Medical University
关键词
呼吸机相关性肺炎
耐药性
pneumonia,ventilator-associated
resistanc e
