摘要
对自主研制的离心式磁悬浮血泵,为分析研究其溶血性能,对其内流场进行建模,在Fluent中进行计算流体力学分析;搭建体外溶血实验装置,在设计工况下,测量一定时间间隔内血浆中游离蛋白含量及红细胞压积,计算出血泵的标准溶血指数。数值模拟结果显示血泵整个流道内静压力分布均匀,各流道间过渡平稳;内部壁面剪切力均在150 Pa以下,红细胞发生破坏与暴露时间无关。体外溶血实验得到标准溶血指数NIH值为(0.002 9±0.000 7)mg/L,符合人类生理学要求。
In order to analyze and study the hemolysis performance of the centrifugal maglev blood pump, which was designed by ourselves, this paper built the mathematical model and computational fluid dynamics analyzed it using Fluent. Then we set up the in vitro hemolysis experiment platform, in case of the design condition, the content of free hemoglobin and hematocrit in plasma were measured in a certain time interval, and calculated the normalized index of hemolysis of the blood pump. The numerical simulation results show the internal static pressure distribution is smooth inside the pump, the wall shear stress inside the pump is less than 150 Pa. Therefore, the red blood cell damage and exposure time is independent. The normalized index of hemolysis is(0.002 9±0.000 7) mg/L, which is in accordance with human physiological requirement.
出处
《中国医疗器械杂志》
2016年第3期169-172,共4页
Chinese Journal of Medical Instrumentation
关键词
磁悬浮血泵
溶血性能
计算流体力学
体外溶血实验
maglev blood pump
hemolysis performance
computational fluid dynamics
in vitro hemolysis experiment
