摘要
将左心模型与四元件的动脉系统Windkessel模型耦合,构成左心-动脉系统交互的左心循环系统模型。模型包括左心房、左心室、二尖瓣、动脉瓣和动脉系统,实现了对左心循环系统的血流动力学模拟。应用状态空间法和SIMULINK框图模型法两种技术和MATLAB工具,进行了数学建模和数值计算,具有模型直观、容易实现、方便调节参数等优点。应用这一仿真模型,可以对左心室容积、血压及主动脉血压和血流等进行动态模拟。仿真结果与生理实际情况相符。
This article demonstrated how a model of left heart can be coupled lo a four-element windkessel model of the arterial system to yield a model of left heart-arterial interaction, The model contains left ventricle （LV）, left atrium, systemic circulation, aortic valve and mitral valve; it simulated the hemodynamics phenomena of left heart circulation. We discussed how to construct the mathematic model of left heart circulation by using MATLAB, gave two methods （state-space method and SIMULINK schematics）. We obtained waveforms of LV volume, LV pressure, aortic pressure and aortic flow after simulation. These waveforms accorded with real physiological conditions.
出处
《中国医学物理学杂志》
CSCD
2005年第6期730-732,716,共4页
Chinese Journal of Medical Physics
基金
广东省自然科学基金资助项目(04020048)
关键词
建模
时变弹性
左心循环
MATLAB
modeling
time-varying elastance
left heart circulation
MATLAB
