摘要
目的 观察颈内动脉系统短暂性脑缺血发作(TIA)的患者在症状消失后是否遗留记忆障碍;并探讨颈内动脉狭窄、TIA的病程,次数及持续时间的长短对记忆功能的影响。方法 35例颈内动脉系统TIA患者在末次发作后平均(8±6)天接受临床记忆量表(甲套)的测试,61名正常对照者也接受同样的量表测试。结果(1)TIA患者的记忆商(memory quotient,MQ),总量表分及其指向记忆、联想学习、图像自由回忆和人像特点联系回忆项的等值量表分与正常对照相比,均有明显下降,而两组在无意义图形再认项的评分上无显著性差异(P>0.05)(2)TIA组内伴颈内动脉狭窄者的总量表分和无意义图形再认项的等值量表分均明显低于无狭窄者(P<0.05)。(3)TIA的病程、发作次数及持续时间的长短与临床记忆量表的MQ及各项等值量表分之间均无明显的相关性(P>0.05)。结论(1)颈内动脉系统TIA患者在症状消失后可遗留不同程度的短时记忆障碍。(2)伴颈内动脉狭窄的TIA患者与无狭窄者相比短时记忆尤其是视觉记忆损害更重。(3)TIA患者的病程、发作次数及每次发作持续时间的长短对记忆功能无明显影响。
Objective To observe whether there were memory deficits in palients following transient ischemic attacks in internal carotid artery (ICA) system and explore the influence of ICA stenosis, course, TIA times, and duration on momory function. Methods Thirty-live ICA TIA patients were tested using clinical memory scale 8+++++++++++6 days alter last TIA and 61 normal controls were tested using the same method. Results (1)As compared with the normal controls, memory quolients(MQ), equivalent scale scores of the lotal scale and pointing memory, association learning, free picture recall, and portrait character association recall items were significantly decreased in ICA TIA patients (all P value were P < 0.01 , except free picture recall was P< 0.05), however, there was no significant difference in insignificant figure recognition item between the two groups (P>0.05).(2)As compared with TIA patients without ICA stenosis, the equivalent scale scores of the total scale and it's insignificant figure recognition were significant decreased in TIA with ICA stenosis ( P < 0.05). (3)There were no significant correlation between course, limes, duration of TIA and MQ, and all the equivalent scale scores of clinical memory scale ( P > 0.05). Conclusions (1)Some degree of short-term memory deficits did exist in ICA TIA patients. (2)Short-term memory especially the visual memory might be impaired more seriously in TIA with ICA stenosis than those without stenosis. (3)The course, limes and duration of TIA had no significant influence on memory function in ICA TIA patients.
出处
《中国神经精神疾病杂志》
CAS
CSCD
北大核心
2003年第6期421-423,共3页
Chinese Journal of Nervous and Mental Diseases
