摘要
目的 :观察脑血宝制剂对血液凝固与纤溶活性的影响。方法 :血栓形成后应用脑血宝制剂(3个剂量组 ) ,观察颈总动脉内栓子的变化和血浆中纤维蛋白 (FIB)、凝血酶时间 (TT)以及体外实验中血液凝固时间及血凝块直径的变化。结果 :应用脑血宝制剂后血凝时间延长 ,血凝块直径缩小 ,颈动脉栓子有溶解的表现 ;血浆中 FIB含量下降 ,TT延长 ,二者有负相关关系。纤溶酶原 (PL G)无明显变化。结论 :脑血宝有溶栓作用 ,但其溶栓作用与激活纤溶酶无关。
? Objective:To observe the thrombolytic effect of Naoxuebao in vitro and in vivo.Methods:The changes of thrombus in the carotid arterial,plasma fibrinogen (FIB),thrombin time (TT) and the diameter of blood clot were observed using Naoxuebao (three dose groups) after thrombosis.Results:With Naoxuebao,the time of blood clot was longer,the diameter of blood clot was shortened;carotid arterial thrombosis was dissolved.The contents of FIB decreased,TT was longer,and FIB and TT had negative correlation;whereas,PLG had no obious change.Conclusion:Naoxuebao had thrombolytic effect,but the effect had no relation with plasmin activating. 〔
出处
《白求恩医科大学学报》
CAS
CSCD
北大核心
2001年第1期33-34,共2页
Journal of Norman Bethune University of Medical Science
