摘要
目的:探讨脑卒中患者智能状况及其影响因素,为减少和避免脑卒中患者智能障碍提供依据。方法:200例脑卒中患者犤男124例,女76例;平均年龄(66±10)岁犦均给予实验室检查及头颅CT扫描,测量病灶范围,计算病灶容积。病程1个月后进行神经功能缺损评分和简易精神状态检查法(MMSE)结合Hachinski缺血指数诊断血管性痴呆,应用汉密顿抑郁量表排除严重抑郁患者。比较痴呆组和非痴呆组患者临床资料、实验室和CT检查结果。结果:脑卒中后痴呆患者占36.5%(73/200)。痴呆组患者年龄犤(69±5)岁犦、神经功能缺损评分(27±10)分,高于非痴呆组(63±7)岁、(12±8)分(F=8.95,11.34,P<0.05)。痴呆组患者受教育≤6年者65.8%(48/73),非痴呆组仅为43.3%(55/127)(χ2=6.11,P<0.05)。痴呆组患者既往有高血压、糖尿病、脑卒中史者高于非痴呆组(87.7%,54.8%,38.4%比62.2%,26.8%,19.7%,χ2=6.15,9.47,9.95,P<0.05)。痴呆组患者血糖、三酰甘油、胆固醇和纤维蛋白原均高于非痴呆组(F=4.96～5.62,P<0.05)。CT显示痴呆组病灶多为多灶(63%比33.9%),病灶容积显著大于非痴呆组(χ2=6.46～7.07,P<0.05)。结论:脑卒中后痴呆是多种因素相互影响的结果,智能障碍与年龄大及神经功能缺损程度相关;与文化程度低和既往有高血压、糖尿病、脑卒中史相关;?
AIM:To study the status and effect factors of intelligence in patients with st roke for the treatment of intelligence dysfunction. METHODS:Two hundred patients with stroke, including 124 males and 76 females w ith an average age of (66±10) years, received laboratory examination and skull CT scan, and all patients were selected without serious depression according to Hamilton depression rating scale. Neurologic impairment score, mini-mental stat e examination (MMSE) and Hachinski ischemia index were used to diagnose vascular dementia for the patients with the time of 1 month after stroke.The data were c ompared between the groups with dementia and without dementia. RESULTS:Dementia was found in 73 of the 200 patients with stroke (36.5 %).The patients with dementia were significantly higher in the average age [(69±5) ye ars] and MMSE score (27±10) than the patients without dementia [(63±7) years, (12±8)] (F=8.95,11.34,P< 0.05). The percentage of receiving education≤6 year s was 65.8%(48/73)for the patients with dementia and 43.3%(55/127)for the patients without dementia (,P< 0.05).The percentages of the patients with the history of hypertension, diabetes mellitus in the dementia group were 8 7.7%, 54.8%and 38.4%respectively, greatly higher than those of the group with out dementia (62.2%,26.8%and 19.7%respectively,,P< 0.0 5). The contents of blood sugar, triacylglycerol and cholesterol and fibrinogen were significantly higher in the group with dementia than in the group without d ementia (F=4.96-5.62,P< 0.05).CT scan showed that the percentage of focus was 63%in the dementia group, significantly higher than in the group without dement ia (33.9%), and focal size of the patients with dementia was bigger than that o f the patients without dementia (-7.07,P< 0.05).
出处
《中国临床康复》
CSCD
2003年第25期3486-3487,共2页
Chinese Journal of Clinical Rehabilitation
关键词
脑卒中
智能状况
文化程度
基础疾病
Dementia in patients with stroke results from the interaction of va rious factors. Intelligence disorder is correlated with age, the severity of neu rologic impairment, low education level, the history of hypertension, diabetes m ellitus and st
