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他汀类药物对血管平滑肌细胞增殖的抑制机制 被引量:7

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出处 《医学综述》 2003年第9期567-568,共2页 Medical Recapitulate
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  • 1Vincent L, Chen W, Hong L, et al. Inhibition of endothelial cell migration by cerivastatin, an HMG-CoA reductase inhibitor: contribution to its anti-angiogenic effect[J]. FEBS Lett.2001.495(3):159-166.
  • 2Negre AP,Van EM, Van LRE, et al. Differential effect of simvastatin on various signal transduction intermediates in cultured human smooth muscle cells[J]. Biochem Pharmaco1,2001,61(8):991-998.
  • 3Hausding M ,Witteck A, Rodriguez Pascual F, et al. Inhibition of small G proteins of the rho family by statins or clostridium difficile toxin B enhances cytokine-mediated induction of NO synthase Ⅱ[J]. Br J Pharmacol, 2000,131(3):553-561.
  • 4Sata M, Nishimatsu H, Suzuki E, et al. Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia[J]. FASEB J,2001,15(13):2530-2532.
  • 5Johnson JL, van Eys GJ, Angelini GD, et al. Injury induces dedifferentiation of smooth muscle cells and increased matrix-degrading metalloproteinase activity in human saphenous vein[J]. Arterioscler Thromb Vasc Biol,2001,21(7):1146-1151.
  • 6Hiroyasu U, Jong DL, Hiromasa S, et al. The roll of protein-tyrosine phosphorylation and gelatinase production in the migration and proliferation of smooth muscle cells[J]. Atherosclerosis, 2000,149(1): 51-59.
  • 7Yasunari K, Maeda K, Minami M, et al. HMG-CoA reductase inhibitors prevent migration human coronary smooth muscle cells through suppression of increase in oxidative stress[J]. Arterioscler Thromb Vasc Biol,2001,21(6):937-942.
  • 8Laufs U, Marra D, Node K, et al. 3-hydroxy -3methylglutaryl-CoA reductase inhibitors attenuate smooth muscle cells proliferation by preventing rho GTPase-induced down- regulation of p27 (Kipl)[J]. J Boll Chem, 1999,274(31) :926-931.
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