摘要
目的 探讨中药通心络对鸡胚绒毛尿囊膜 (CAM)模型血管生成作用的影响。方法 运用血清药理学的方法制备药物血清 ,鸡胚随机分为空白血清组、贝复济组及通心络大、小剂量组 ,检测尿囊膜的血管增生程度。结果 通心络大剂量组CAM的血管增生数明显高于空白血清组 (P <0 .0 5) ,而与贝复济组无明显差异 (P >0 .0 5) ;通心络小剂量组与空白血清组相比无明显差异 (P >0 .0 5)。结论 通心络可促进鸡胚绒毛尿囊膜的血管增生 。
Objective To study the stimulate angiogenes effect of Tongxinluo capsule on the chick embryo chorioallantoic membrane (CAM) model.Methods 32 chick embryo (CE) were randomly divided into 4 groups,8 CE in group A were treated with vacuity blood serum as negative controls,8 CE in group B were treated with basic Fibroblast Growth Facter as positive controls,8 CE in group C and 8 CE in group D were treated with maxiums and micro dose of Tongxinluo herbal serum respectively.After 3 days of incubated,count the first and second grade vessels.Results The proliferation of vessels in group C was obviously increase than that in group A (P<0.05) and almost equaled to that of group B (P>0.05),but group D has no obviously difference compared with group A (P> 0.05 ).Conclusion Tongxinluo capsule can stimulate angiogenesis of the Chick embryo CAM model.
出处
《疑难病杂志》
CAS
2003年第1期2-4,F003,共4页
Chinese Journal of Difficult and Complicated Cases
