摘要
左金丸载于《丹溪心法》,该方由黄连和吴茱萸组成,具有抗菌抗炎、修复胃黏膜损伤、抗肿瘤、调节免疫功能、调节胃肠功能等药理作用,常用于治疗胃食管反流病、功能性消化不良、慢性胃炎、溃疡性结肠炎、肠易激综合征等消化系统疾病。本文通过整理近年来有关左金丸的研究结果,系统阐述该方的单味药物和组方的有效成分、药理作用及其在消化系统疾病治疗中的研究进展,以期为左金丸复方的深入研究,以及左金丸在消化系统疾病临床扩展应用提供参考。
Zuojin Pills,recorded in Danxi Xinfa(a classic of Traditional Chinese Medicine from Yuan dynasty),is composed of Coptis chinensis and Evodia rutaecarpa.It possesses pharmacological effects such as antibacterial and anti-inflammatory actions,repair of gastric mucosal damage,antitumor activity,regulation of immune function,and modulation of gastrointestinal function.Clinically,it is commonly used to treat digestive system diseases including gastroesophageal reflux disease,functional dyspepsia,chronic gastritis,ulcerative colitis,and irritable bowel syndrome.By reviewing recent research findings on Zuojin Pills,this paper systematically elaborates on the active components,pharmacological effects of both the individual herbs and the formula,as well as the research progress on its treatment for digestive system diseases,aiming to provide references for further in-depth study of the Zuojin Pills compound and its expanded clinical application in digestive system diseases.
作者
徐娇
刘礼剑
黎丽群
谢丽丽
李桂芳
XU Jiao;LIU Lijian;LI Liqun;XIE Lili;LI Guifang(Graduate School,Guangxi University of Chinese Medicine,Nanning 530001,Guangxi,China;Department of Spleen and Stomach Diseases,the First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,Guangxi,China)
出处
《广西医学》
2025年第12期1733-1738,共6页
Guangxi Medical Journal
基金
国家自然科学基金地区科学基金项目(82160877)。
关键词
左金丸
化学成分
药理作用
消化系统疾病
综述
Zuojin Pills
Chemical components
Pharmacological effects
Digestive system diseases
Review
