摘要
目的探讨水杨酸外涂及点阵激光联合治疗对痤疮患者的影响。方法选取2022年3月至2025年3月濮阳市第二人民医院收治的122例痤疮患者,按治疗方法不同分为两组,各61例。对照组予以点阵激光治疗,观察组在对照组基础上加用水杨酸外涂。两组均治疗8周。对比两组疗效、皮损计数情况、皮肤状况、生活质量、不良反应。结果观察组临床总有效率高于对照组,差异有统计学意义(P<0.05);治疗后,观察组皮损计数均少于对照组,角质层含水量以及各项痤疮特异性生活质量问卷(Acne-QO)评分均高于对照组,皮脂分泌量、红斑指数、经皮水分流失量均低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率相当,差异无统计学意义(P>0.05)。结论水杨酸外涂联合点阵激光治疗痤疮疗效显著,可减少皮损数量,改善皮肤状况,提高生活质量,且不增加不良反应。
Objective To explore the effect of topical application of salicylic acid and fractional laser on acne patients.Methods A total of 122 cases of acne who admitted to Puyang Second People's Hospital from March 2022 to March 2025 were taken as the objects.All cases were assigned to two groups(61 cases each)based on different treatment regimens.The patients of control group were administrated fractional laser,and on this basis,the patients of observation group additionally took topical application of salicylic acid for 8 weeks.The comparisons were performed on efficacy,lesion count,skin condition,quality of life,and adverse reactionsin both groups.Results The observation group obtained higher overall effective rate than the control group(P<0.05);Compared with the control group,the observation group had less lesion count,higher water content of stratum corneum and scores of all dimension of the Acne-specific Quality of Life Assessment(Acne-QO),lower sebum secretion,erythema index and trans-epidermal water loss after treatment(P<0.05);The two groups achieved comparable incidence of adverse reactions,which expressed no statistical difference(P>0.05).Conclusions The combined regimen of topical application of salicylic acid and fractional laser has significant efficacy on acne.It can reduce the number of skin lesions,improve skin condition,enhance the quality of life,and does not increase adverse reactions.
作者
吴晓丽
吴媛媛
WU Xiaoli;WU Yuanyuan(Department of Medical Aesthetics,Puyang Second People's Hospital,Puyang 457000,Henan Province,China;Department of Third Ward of Ophthalmology,Puyang Second People's Hospital,Puyang 457000,Henan Province,China)
出处
《中国医疗美容》
2025年第11期6-11,共6页
China Medical Cosmetology
关键词
痤疮
点阵激光
水杨酸
皮肤状况
疗效
acne
fractional laser
salicylic acid
skin condition
efficacy
