摘要
目的探讨中医微创针刀镜治疗慢性痛风性关节炎的临床疗效及安全性。方法选择2020年1月至2025年1月在苏州高新区人民医院就诊的96例慢性痛风性关节炎患者,采用随机数表法将患者分为研究组和对照组,每组48例。研究组采用中医微创针刀镜治疗,对照组采用常规手术治疗。比较两组疗效以及治疗前后实验室指标[血尿酸、C反应蛋白(CRP)、红细胞沉降率(ESR)水平]和结局指标[Lysholm评分、疼痛视觉模拟评分法(VAS)评分],随访至患者出院后6个月,观察患者不良反应或并发症发生情况。结果研究组治疗总有效率高于对照组[97.92%(47/48)比85.42%(41/48)](χ^(2)=4.909,P=0.027)。两组治疗前血尿酸、CRP、ESR水平以及Lysholm评分、VAS评分比较差异无统计学意义(P>0.05)。治疗4周后,两组血尿酸、CRP、ESR水平以及VAS评分均降低,Lysholm评分均升高,且研究组血尿酸、CRP、ESR水平以及VAS评分均低于对照组[(37±12)μmol/L比(45±14)μmol/L、(16.7±4.2)mg/L比(23.6±3.8)mg/L、(427±72)mm/1 h比(486±86)mm/1 h、(2.3±0.7)分比(2.8±0.7)分](P<0.01),而Lysholm评分高于对照组[(48±16)分比(41±13)分](P<0.05)。治疗后两组均未发生明显不良反应或并发症;出院后随访6个月,所有患者状况良好,无复发病例。结论中医微创针刀镜术治疗慢性痛风性关节炎疗效显著,且安全性良好。
Objective To explore the clinical efficacy and safety of minimally invasive needle-knife endoscopy in traditional Chinese medicine in the treatment of chronic gouty arthritis.MethodsA total of 96 patients with chronic gouty arthritis who visited Suzhou High-tech Zone People's Hospital from Jan.2020 to Jan.2025 were included.The patients were divided into study group and control group by the random number table method,with 48 cases in each group.The study group was treated with minimally invasive needle-knife endoscopy in traditional Chinese medicine,while the control group was treated with conventional surgery.The therapeutic effects and the laboratory indicators[levels of blood uric acid,C-reactive protein(CRP),and erythrocyte sedimentation rate(ESR)]and outcome indicators[Lysholm score,visual analogue scale(VAS)score]before and after treatment of the two groups were compared.The patients were followed up until 6 months after discharge to observe the occurrence of adverse reactions or complications in the patients.ResultsThe total effective rate of treatment in the study group was higher than that in the controlgroup[97.92%(47/48)vs 85.42%(41/48)](χ^(2)=4.909,P=0.027).There was no statistically significant difference in the levels of blood uric acid,CRP,ESR,Lysholm score and VAS score between the two groups before treatment(P>0.05).After 4 weeks of treatment,the levels of blood uric acid,CRP,ESR and VAS scores in both groups decreased,while the Lysholm scores increased.Moreover,the levels of blood uric acid,CRP,ESR and VAS score in the study group were all lower than those in the control group[(37±12)μmol/L vs(45±14)μmol/L,(16.7±4.2)mg/L vs(23.6±3.8)mg/L,(427±72)mm/1 h vs(486±86)mm/1 h,2.3±0.7 vs 2.8±0.7](P<0.01),while the Lysholm score was higher than that of the control group(48±16 vs 41±13)(P<0.05).No obvious adverse reactions or complications occurred in either group after treatment.After discharge,during the 6 months follow-up,all patients were in good condition and there were no recurrent cases.Conclusion The traditional Chinese medicine minimally invasive needle-knife endoscopy has a remarkable therapeutic effect on chronic gouty arthritis with good safety.
作者
金晨凯
谭立辉
陈玉琪
董建建
卫荣
JIN Chenkai;TAN Lihui;CHEN Yuqi;DONG Jianjian;WEI Rong(Department of Rheumatology and Immunology,Suzhou High-tech Zone People's Hospital,Suzhou 215129,China)
出处
《医学综述》
2025年第21期2765-2768,F0003,共5页
Medical Recapitulate
关键词
慢性痛风性关节炎
中医微创针刀镜
临床疗效
Chronic gouty arthritis
Traditional Chinese medicine minimally invasive needle-knifeendoscopy
Clinical efficacy
