摘要
目的探索血清C肽和糖化血红蛋白检验在糖尿病诊断中的应用效果。方法非随机便利选择2021年12月—2023年12月在三明市第二医院就诊的50例糖尿病患者为研究组,选取同期健康体检人群50例为对照组。对比两组糖化血红蛋白、血清C肽水平;分析血清C肽、糖化血红蛋白联合检测的诊断效能。结果研究组糖化血红蛋白、血清C肽水平均高于对照组,差异均有统计学意义(P均<0.05)。血清C肽和糖化血红蛋白联合测定的诊断效能更优,其灵敏度、特异度及准确度更高,差异均有统计学意义(P均<0.05)。结论糖尿病患者血清C肽、糖化血红蛋白存在异常,血清C肽联合糖化血红蛋白测定对糖尿病的诊断具有一定的临床价值。
Objective To explore the application effect of serum C-peptide and glycated hemoglobin A1c test in the diagnosis of diabetes mellitus.Methods From December 2021 to December 2023,50 diabetic patients in the Sanming Second Hospital were selected as the study group,and 50 healthy people in the same period were Non-randomly and conveniently selected as the control group.The levels of glycated hemoglobin A1c and serum C-peptide were compared in the two groups,the diagnostic efficacy of combined detection of serum C-peptide and glycated hemoglobin A1c was analyzed.Results The levels of glycated hemoglobin A1c and serum C peptide in the study group were higher than those in the control group,and the differences were statistically significant(both P<0.05).The combined determination of serum C-peptide and glycated hemoglobin A1c had better diagnostic efficacy,higher sensitivity,specificity and accuracy,and the differences were statistically significant(all P<0.05).Conclusion There are abnormalities in serum C-peptide and glycated hemoglobin A1c in diabetic patients,serum C-peptide combined with glycosylated hemoglobin has certain clinical value in the clinical diagnosis of diabetes mellitus.
作者
卢涛
殷小猛
邓鹏飞
LU Tao;YIN Xiaomeng;DENG Pengfei(Sanming Second Hospital,Sanming 366000,Fujian,China;Yong'an Municipal Hospital,Sanming 366000,Fujian,China)
出处
《糖尿病新世界》
2025年第21期81-84,共4页
Diabetes New World
关键词
血清C肽
糖化血红蛋白
糖尿病
诊断效能
Serum C-peptide
Glycated hemoglobin A1c
Diabetes mellitus
Diagnostic efficiency
