摘要
肌少症在肝硬化病人中发病率高,严重影响病人生活质量及生存率。其发病机制与营养摄入不足、激素水平异常、高氨水平、炎症因子水平异常、菌群失调及缺乏运动等有关。本文将从肝硬化肌少症流行病学特征、发病机制、筛查及诊断、治疗进行综述,帮助医生及病人更好地进行肌少症的预防、监测和干预。
Sarcopenia is common in patients with cirrhosis and significantly impacts their quality of life and survival.Its pathogenesis involves multiple factors,including inadequate nutrient intake,abnormal hormone levels,high ammonia levels,abnormal levels of inflammatory factors,imbalanced gut bacteria,and physical inactivity.This study aims to review the epidemiological characteristics,pathogenesis,screening,diagnosis,and treatment of cirrhosis to assist doctors and patients in better preventing,monitoring,and addressing sarcopenia.
作者
董洋
巩尧瑶
程文芳
DONG Yang;GONG Yao-yao;CHENG Wen-fang(Department of Gastroenterology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,Jiangsu,China)
出处
《肠外与肠内营养》
北大核心
2025年第4期240-245,共6页
Parenteral & Enteral Nutrition
基金
重庆市自然科学基金(CSTB2025NSCQ-GPX0452)
綦江区自然科学基金(2025059)。
关键词
肝硬化
肌少症
发病机制
诊断
治疗
Cirrhosis
Sarcopenia
Pathogenesis
Diagnosis
Treatment
